Mora-Fenoll, María Teresa; Gomez, Juan F.; Morley, Gregory; Ferrero De Loma-Osorio, José María; Trenor Gomis, Beatriz Ana(Public Library of Science, 2019-06-18)
[EN] Heart failure (HF) is characterized, among other factors, by a progressive loss of contractile function and by the formation of an arrhythmogenic substrate, both aspects partially related to intracellular Ca2+ cycling ...
[EN] Potassium levels in the plasma, [Kþ]o, are regulated precisely under physiological conditions. However, increases (from approx. 4.5 to
8.0 mM) can occur as a consequence of, e.g., endurance exercise, ischemic insult ...
Holzem, Katherine M.; Gómez García, Juan Francisco; Glukhov, Alexey V.; Madden, Eli J.; Koppel, Aaron C.; Ewald, Gregory A.; Trénor Gomis, Beatriz Ana; Efimov, Igor R.(Elsevier, 2016-07)
Heart failure (HF) claims 250,000 lives per year in the US, and nearly half of these deaths are sudden and presumably
due to ventricular tachyarrhythmias. QT interval and action potential (AP) prolongation are hallmark ...