[EN] The biological behaviour of Schwann cells (SCs) and dorsal root ganglia (DRG) on fibrillar, highly aligned and electroconductive substrates obtained by two different techniques is studied. Mats formed by nanometer-sized ...
Serrano Requena, Sara(Universitat Politècnica de València, 2021-10-08)
[ES] Las patologías que se derivan en el sistema nervioso llevan asociadas la dificultad de regeneración del propio tejido, especialmente cuando se habla del Sistema Nervioso Central (SNC). Es debido a esta problemática ...
García Castelló, Marcos(Universitat Politècnica de València, 2019-09-17)
[ES] La regeneración neuronal ha ido tomando importancia con el paso del tiempo y con ella, las aplicaciones en la ingeniería tisular. Además, se ha demostrado en múltiples artículos, como el uso de células de Schwann ...
[EN] Nerve regeneration is a slow process that needs to be guided for distances greater than 5 mm. For this reason, different strategies are being studied to guide axonal growth and accelerate the axonal growth rate. In ...
Bolaina-Lorenzo, Ena; Martínez-Ramos, Cristina; Monleón Pradas, Manuel; Herrera-Kao, Wilberth; Cauich-Rodríguez, Juan V; Cervantes-Uc, José M(IOP Publishing, 2017)
[EN] Electrospun polycaprolactone (PCL)/chitosan (CH) blend scaffolds with different CH weight ratios were prepared to study the effect of scaffold composition on its physicochemical and biological properties. Scanning ...
Gisbert Roca, Fernando; Gil Santos, Luis; Mata Roig, Manuel; Milian Medina, Lara; Martínez-Ramos, Cristina; Monleón Pradas, Manuel(MDPI AG, 2022-05)
[EN] The gold standard for the treatment of peripheral nerve injuries, the autograft, presents several drawbacks, and engineered constructs are currently suitable only for short gaps or small diameter nerves. Here, we study ...
Andreu Oller, Carmen(Universitat Politècnica de València, 2014-09-19)
[ES] Las patologías del sistema nervioso central y periférico tienen una gran incidencia sobre la población (consecuencias del ictus, enfermedades neurodegenerativas como el Parkinson, trauma, tumores) y aguardan nuevos ...
Rodríguez Pérez, Eduard; García Cruz, Dunia Mercedes; Araque Monrós, María Carmen; Gómez Pinedo, Ulises; Monleón Pradas, Manuel; Escobar Ivirico, Jorge Luis(SAGE Publications, 2013)
[EN] This study describes a strategy for the covalent immobilization of active adhesion peptide moieties onto polymers through the intermediacy of itaconic acid. The arginine-glycine-aspartic acid peptide was grafted to a ...
Mukhatyar, Vivek J.; Salmerón Sánchez, Manuel; Rudra, Soumon; Mukhopadaya, Shoumit; Barker, Thomas H.; Garcia, Andres J.; Bellamkonda, Ravi V.(Elsevier, 2011)
Bridging of long peripheral nerve gaps remains a significant clinical challenge. Electrospun nanofibers have been used to direct and enhance neurite extension in vitro and in vivo. While it is well established that oriented ...