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Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence

Mangas-Sanjuan, Victor; Pleguezuelos-Villa, María; Merino-Sanjuán, Matilde; Hernández, Mª Jesús; Nácher, Amparo; García-Arieta, Alfredo; Peris, Daniel; Hidalgo, Irene; Soler, Lluís; Sallan, Marta; Merino, Virginia (MDPI AG, 2019-10)

[EN] Demonstration of similar microstructure is essential for demonstrating the equivalence of generic topical products since the microstructure of semisolids may affect the drug release. The objective of this study was ...
Environmentally sensitive fluorescence of the topical retinoid adapalene

Soler-Orenes, Juan A.; Monari, Antonio; Miranda, Miguel A.; Hernández-Gil, Javier; Lhiaubet, Virginie Lyria (Frontiers Media SA, 2024-07-08)

[EN] Intrinsic fluorescence of drugs brings valuable information on their localization in the organism and their interaction with key biomolecules. In this work, we investigate the absorption and emission properties of the ...

Mostrando ítems 1-2 de 2