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Computational modeling of the zebrafish heart

Bataller Martínez, Marina (Universitat Politècnica de València, 2022-09-19)

[ES] Es sabido desde hace algunos años que el corazón del pez cebra puede utilizarse como modelo animal para la electrofisiología cardíaca humana. Esto es debido a la enorme similitud que existe entre el potencial de acción ...
Macrophage-Dependent Interleukin-6-Production and Inhibition of I-K Contributes to Acquired QT Prolongation in Lipotoxic Guinea Pig Heart

Chowdhury, Md. Kamrul Hasan; Martínez-Mateu, Laura; Do, Jenny; Aromolaran, Kelly A.; Saiz Rodríguez, Francisco Javier; Aromolaran, Ademuyiwa (MDPI AG, 2021-10)

[EN] In the heart, the delayed rectifier K current, I-K, composed of the rapid (I-Kr) and slow (I-Ks) components contributes prominently to normal cardiac repolarization. In lipotoxicity, chronic elevation of pro-inflammatory ...
Mechanistic investigation of Ca2+ alternans in human heart failure and its modulation by fibroblasts

Mora-Fenoll, María Teresa; Gomez, Juan F.; Morley, Gregory; Ferrero De Loma-Osorio, José María; Trenor Gomis, Beatriz Ana (Public Library of Science, 2019-06-18)

[EN] Heart failure (HF) is characterized, among other factors, by a progressive loss of contractile function and by the formation of an arrhythmogenic substrate, both aspects partially related to intracellular Ca2+ cycling ...

Mostrando ítems 1-3 de 3