[EN] Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal beta-galactosidase ...
[EN] Background: Platinum doublets are standard chemotherapy for advanced non-small-cell lung cancer (NSCLC). The aim of this study was to assess whether neutropenia is: (1) an indicator for treatment efficacy, or (2) ...
[EN] Hydrogels are widely studied as drug delivery system. In this work we propose the employment of tetrakis (hydroxymethyl)phosphonium chloride as crosslinking agent to obtain covalent hydrogels based on chitosan. These ...
Mínguez García, David(Universitat Politècnica de València, 2020-11-06)
[ES] En el presente proyecto se realiza el estudio y diseño de un gorro hipotérmico para prevenir la alopecia inducida por la quimioterapia. Se trata de un producto que incorporará materiales de cambio de fase (PCMs) en ...
March Yagüe, Aina(Universitat Politècnica de València, 2018-09-18)
[ES] El cáncer es una enfermedad que afecta a gran parte de la población, siendo el cáncer de mama el más frecuentemente diagnosticado en mujeres. Su incidencia está aumentando, siendo hoy en día la principal causa de ...
Hidalgo Villamar, Irene Zulay(Universitat Politècnica de València, 2018-09-12)
[ES] Actualmente el cáncer es una de las enfermedades que más se diagnostica cada día, tanto a nivel nacional como mundial, hasta el punto de ser considerada una epidemia.
Entre los tratamientos para frenarlo se encuentra ...
[EN] Glioblastoma multiforme is one of the most prevalent and malignant forms of central nervous system tumors. The treatment of glioblastoma remains a great challenge due to its location in the intracranial space and the ...
NAVARRO GÓMEZ - LECHÓN, ANA(Universitat Politècnica de València, 2018-07-18)
[ES] Los agentes empleados en los tratamientos quimioterapéuticos pueden afectar al sistema reproductivo
de los pacientes y, por tanto, a su fertilidad. De manera experimental, la criopreservación del tejido
testicular ...
Garde-Noguera, Javier; Fernández-Murga, M. Leonor; Giner-Bosch, Vicent; Domínguez-Márquez, Victoria; García Sánchez, José; Soler-Cataluña, Juan José; López Chuliá, Francisca; Honrubia, Beatriz; Piera, Nuria; Llombart-Cussac, Antonio(MDPI AG, 2020-12)
[EN] Background: Studies of patients with cancer affected by coronavirus disease 2019 (COVID-19) are needed to assess the impact of the disease in this sensitive population, and the influence of different cancer treatments ...
Álvarez-Torres, María del Mar; Fuster García, Elíes; Balaña, Carmen; Puig, Josep; Garcia-Gomez, Juan M(MDPI AG, 2021-11)
[EN] Despite the complete treatment with surgery, chemotherapy and radiotherapy, patients with glioblastoma have a devasting prognosis. Although the role of extending temozolomide treatment has been explored, the results ...
[EN] Patients with lung cancer are especially vulnerable to coronavirus disease 2019 (COVID-19) with a greater than sevenfold higher rate of becoming infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...
Torres Ruiz, Sandra(Universitat Politècnica de València, 2024-09-15)
[ES] El cáncer de mama triple negativo representa el 10-20% de los casos de cáncer de mama. Este subtipo molecular se caracteriza por su gran agresividad y capacidad invasiva y se asocia a un mal pronóstico. La ausencia ...
Gasent Blesa, J. M.; Giner Marco, V.; Giner-Bosch, Vicent; Cerezuela Fuentes, Pablo; Alberola Candel, Vicente(Lippincott Williams & Wilkins, 2011)
[EN] Introduction: Docetaxel plus prednisone is the current standard of care in first-line chemotherapy for metastatic hormone-refractory prostate cancer. However, there is no agent proven as effective after progression ...
Rivero-Buceta, Eva María; VIDAURRE AGUT, CARLA MARIA; VERA DONOSO, CESAR DAVID; Benlloch Baviera, Jose María; MORENO MANZANO, VICTORIA; BOTELLA ASUNCION, PABLO(American Chemical Society, 2019-01-31)
[EN] Although docetaxel is currently broadly used in prostate cancer treatment, poor water solubility and systemic toxicity limit the dose and duration of therapy. In this context, although different nanoplatforms have ...