De Diego Damiá, Alfredo; Cortijo Gimeno, Julio; Selma Ferrer, María José; León Fábregas, Montserrat; Almudéver-Folch, Patricia; Milara Payá, Javier(Elsevier, 2011-09)
[EN] Introduction: Cigarette smoke is the main cause of inflammation in COPD. The mechanisms that differentiate smokers who develop COPD are diverse. In this study, we analyzed the presence of cytokines in the
respiratory ...
Andújar Pérez, Isabel; Rios, José Luis; Giner, Rosa María; Cerda, José Miguel; Recio, María del Carmen(Hindawi Publishing Corporation, 2012)
[EN] The naphthoquinone shikonin, a major component of the root of Lithospermum erythrorhizon, now is studied as an anti-inflammatory agent in the treatment of ulcerative colitis (UC). Acute UC was induced in Balb/C mice ...
Boza Cuenca, Marta(Universitat Politècnica de València, 2022-09-06)
[ES] La Enfermedad Inflamatoria Intestinal (EII) es un trastorno inflamatorio crónico debilitante del tracto gastrointestinal, en la cual clasificamos dos enfermedades principales: la colitis ulcerosa (CU) y la enfermedad ...
Pardo Sánchez, José Miguel(Universitat Politècnica de València, 2014-07-31)
[EN] Immunoassays are normally used in order to measure cytokines in patients samples.
Among them, ELISA is the standard technique, though the novel Luminex® xMAP® technology is
more suitable for the new molecular biology ...
Chowdhury, Md. Kamrul Hasan; Martínez-Mateu, Laura; Do, Jenny; Aromolaran, Kelly A.; Saiz Rodríguez, Francisco Javier; Aromolaran, Ademuyiwa(MDPI AG, 2021-10)
[EN] In the heart, the delayed rectifier K current, I-K, composed of the rapid (I-Kr) and slow (I-Ks) components contributes prominently to normal cardiac repolarization. In lipotoxicity, chronic elevation of pro-inflammatory ...
Benito Mallol, Virginia de(Universitat Politècnica de València, 2020-07-11)
[ES] La Enfermedad Inflamatoria Intestinal (EII) engloba principalmente a la colitis ulcerosa (CU) y a la enfermedad de Crohn (EC). Con etiopatogenia aún desconocida, la teoría más extendida es que se produce una respuesta ...
Monsoriu Melero, María del Carmen(Universitat Politècnica de València, 2017-09-26)
[EN] The aim of this study is to evaluate the influence of the angiogenic status of a mixoid
sarcoma on the response to Pazopanib. To this effect, three translational phase II studies were
performed: the first of them ...
Martínez Fernández de la Cámara, Cristina Isabel(Universitat Politècnica de València, 2014-10-30)
[EN] Retinitis Pigmentosa (RP) is a common form of hereditary retinal degeneration characterized by the loss of retinal photoreceptor cells (rods and cones) and constitutes the largest single cause of blindness in the ...
Sierra, Jelver A.; Gilchrist, Katherine; Tabares-Guevara, Jorge H.; Betancur-Galvis, Liliana; Ramírez-Pineda, José R.; González-Cardenete, Miguel A(MDPI AG, 2022-10)
[EN] Abietic acid (AA), dehydroabietic acid (DHA) and triptoquinones (TQs) are bioactive abietane-type diterpenoids, which are present in many edible vegetables and medicinal herbs with health-promoting properties. Evidence ...