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Antineoplastic tropolone derivatives as useful biomarkers: fluorescence enhancement upon binding to biological targets

Tormos Faus, Rosa Esperanza; Bosca Mayans, Francisco (Royal Society of Chemistry, 2013)

It has been observed for the first time that the binding of tropolone derivatives to human serum albumin (HSA) produce a high fluorescence promotion. Important evidence of the immobilization of these drugs into the protein ...
Enhanced photosafety of cinacalcet upon complexation with serum albumin

Nuin Plá, Neus Edurne; Andreu Ros, María Inmaculada; Torres, Maria Jose; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (American Chemical Society, 2011-02-10)

Cinacalcet (CIN) is a calcimimetic drug, which contains a naphthalene chromophore and binds almost quantitatively to human serum albumin (HSA). In the present work, the excited states of CIN have been characterized in order ...
Stereodifferentiation in the intramolecular singlet excited state quenching of hydroxybiphenyl-tryptophan dyads

Bonancía Roca, Paula; Vayá Pérez, Ignacio; Markovitsi, Dimitra; Gustavsson, Thomas; Jiménez Molero, María Consuelo; Miranda Alonso, Miguel Ángel (Royal Society of Chemistry, 2013)

The photochemical processes occurring in diastereomeric dyads (S, S)-1 and (S, R)-1, prepared by conjugation of (S)-2-(2-hydroxy-1,1'-biphenyl-4-yl) propanoic acid ((S)-BPOH) with (S)- and (R)-Trp, have been investigated. ...

Mostrando ítems 1-3 de 3