[EN] A previously validated constraint based model and possibilistic MFA have been used to design a simple estimator of protein production rate in Pichia pastoris cultures. A structured model of the yeast P. pastoris ...
Llaneras Estrada, Francisco(Universitat Politècnica de València, 2011-03-23)
This thesis is devoted to the study and application of constraint-based metabolic models. The objective was to find simple ways to handle the difficulties that arise in practice due to uncertainty (knowledge is incomplete, ...
Folch-Fortuny, Abel; Tortajada Serra, Marta; Prats-Montalbán, José Manuel; Llaneras Estrada, Francisco; Picó Marco, Jesús Andrés; Ferrer Riquelme, Alberto José(Elsevier, 2015-03-15)
[EN] With the aim of understanding the flux distributions across a metabolic network, i.e. within living cells, Principal Component Analysis (PCA) has been proposed to obtain a set of orthogonal components (pathways) ...
Tortajada Serra, Marta(Universitat Politècnica de València, 2012-07-23)
El objetivo general de la presente tesis doctoral es el desarrollo de herramientas para la
obtencion, produccion y aplicacion de dos enzimas glicosidicas: �¿-L-arabinofuranosidasa
proveniente del hongo Aspergillus niger ...
Background: Constraint-based metabolic models and flux balance analysis (FBA) have been extensively used in the last years to investigate the behavior of cells and also as basis for different industrial applications. In ...