[EN] Senescent cells accumulate in multiple aging-associated diseases, and eliminating these cells has recently emerged as a promising therapeutic approach. Here, we take advantage of the high lysosomal beta-galactosidase ...

[ES] La enfermedad de Crohn (EC) es una patología inflamatoria multifactorial, crónica y recidivante del tracto gastrointestinal. En un alto porcentaje de pacientes, la enfermedad se asocia con complicaciones como la ...

[EN] Triple-negative breast cancer (TNBC) is a very aggressive subtype of breast cancer with a poor prognosis and limited effective therapeutic options. Induction of senescence, arrest of cell proliferation, has been ...

[ES] Los últimos avances acerca de la senescencia celular ponen en evidencia su relación con un amplio rango de enfermedades entre las que se incluye el cáncer, colocando a este proceso como una potencial diana terapéutica. ...

[EN] The induction of senescence produces a stable cell cycle arrest in cancer cells, thereby inhibiting tumor growth; however, the incomplete immune cell-mediated clearance of senescent cells may favor tumor relapse, ...