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Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorns delivered siRNA.

Pérez-Martínez, Francisco C.; Carrión, Blanca; Lucío, María Isabel; Rubio, Noelia; Herrero, Maria A.; Vázquez, Ester; Ceña, Valentín (Elsevier, 2012-11)

[EN] We synthesized a non-viral delivery system (f-CNH3) for small interfering RNA (siRNA) by anchoring a fourth-generation polyamidoamine dendrimer (G4-PAMAM) to carbon nanohorns (CNHs). Using this new compound, we delivered ...
Unique functionality of 22-nt miRNAs in triggering RDR6-dependent siRNA biogenesis from target transcripts in Arabidopsis

Cuperus, Josh T.; CARBONELL, ALBERTO; Fahlgren, Noah; Garcia-Ruiz, Hernan; Burke, Russell T.; Takeda, Atsushi; Sullivan, Christopher M.; Gilbert, Sunny D.; Montgomery, Taiowa A.; Carrington, James C. (Nature Publishing Group, 2010-08)

[EN] NA interference pathways can involve amplification of secondary siRNAs by RNA-dependent RNA polymerases. In plants, RDR6-dependent secondary siRNAs arise from transcripts targeted by some microRNAs (miRNAs). Here, ...

Mostrando ítems 1-2 de 2