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dc.contributor.author | FLORES PEDAUYE, RICARDO | es_ES |
dc.contributor.author | Delgado Villar, Sonia Guadalupe | es_ES |
dc.contributor.author | Gas, María-Eugenia | es_ES |
dc.contributor.author | CARBONELL, ALBERTO | es_ES |
dc.contributor.author | Molina, Diego | es_ES |
dc.contributor.author | Gago, Selma | es_ES |
dc.contributor.author | La Peña Del Rivero, Marcos De | es_ES |
dc.date.accessioned | 2024-01-24T19:03:20Z | |
dc.date.available | 2024-01-24T19:03:20Z | |
dc.date.issued | 2004-06-01 | es_ES |
dc.identifier.issn | 0014-5793 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/202130 | |
dc.description.abstract | [EN] Viroids are small (246¿401 nucleotides), non-coding, circular RNAs able to replicate autonomously in certain plants. Viroids are classified into the families Pospiviroidae and Avsunviroidae, whose members replicate in the nucleus and chloroplast, respectively. Replication occurs by an RNA-based rolling-circle mechanism in three steps: (1) synthesis of longerthan-unit strands catalyzed by host DNA-dependent RNA polymerases forced to transcribe RNA templates, (2) processing to unit-length, which in family Avsunviroidae is mediated by hammerhead ribozymes, and (3) circularization either through an RNA ligase or autocatalytically. Disease induction might result from the accumulation of viroid-specific small interfering RNAs that, via RNA silencing, could interfere with normal developmental pathways. | es_ES |
dc.description.sponsorship | This work was partially supported by grants from the Ministerio de Ciencia y Tecnologia (BMC2002-03694) and from the Generalidad Valenciana (Spain). | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | John Wiley & Sons | es_ES |
dc.relation.ispartof | FEBS Letters | es_ES |
dc.rights | Reserva de todos los derechos | es_ES |
dc.subject | Viroid | es_ES |
dc.subject | Catalytic RNA | es_ES |
dc.subject | Hammerhead ribozyme | es_ES |
dc.subject | RNA silencing | es_ES |
dc.title | Viroids: the minimal non-coding RNAs with autonomous replication | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1016/j.febslet.2004.03.118 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MICYT//BMC2002-03694/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química | es_ES |
dc.description.bibliographicCitation | Flores Pedauye, R.; Delgado Villar, SG.; Gas, M.; Carbonell, A.; Molina, D.; Gago, S.; La Peña Del Rivero, MD. (2004). Viroids: the minimal non-coding RNAs with autonomous replication. FEBS Letters. 567(1):42-48. https://doi.org/10.1016/j.febslet.2004.03.118 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1016/j.febslet.2004.03.118 | es_ES |
dc.description.upvformatpinicio | 42 | es_ES |
dc.description.upvformatpfin | 48 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 567 | es_ES |
dc.description.issue | 1 | es_ES |
dc.identifier.pmid | 15165891 | es_ES |
dc.relation.pasarela | S\26478 | es_ES |
dc.contributor.funder | Generalitat Valenciana | es_ES |
dc.contributor.funder | Ministerio de Ciencia y Tecnología | es_ES |