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dc.contributor.author | Français, Antonio | es_ES |
dc.contributor.author | Leyva Perez, Antonio | es_ES |
dc.contributor.author | Etxebarria-Jardi, Gorka | es_ES |
dc.contributor.author | Peña, Javier | es_ES |
dc.contributor.author | Ley, Steven V. | es_ES |
dc.date.accessioned | 2013-11-18T13:43:10Z | |
dc.date.issued | 2011-01-03 | |
dc.identifier.issn | 0947-6539 | |
dc.identifier.uri | http://hdl.handle.net/10251/33685 | |
dc.description.abstract | For over five decades, owing to their antiapoptotic activities, bongkrekic and isobongkrekic acids have generated interest from the scientific community. Here, we disclose full details of our investigation into the synthesis of isobongkrekic acid, which culminated in its first preparation and features various palladium-catalysed cross-couplings and Takai olefination reactions. Access to bongkrekic acid is also reported by this route. These syntheses involve the preparation and use of new general building blocks which could find wider applications. | es_ES |
dc.format.extent | 15 | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Wiley-VCH Verlag | es_ES |
dc.relation.ispartof | Chemistry - A European Journal | es_ES |
dc.rights | Reserva de todos los derechos | es_ES |
dc.subject | Anti-apoptotic | es_ES |
dc.subject | Natural products | es_ES |
dc.subject | Palladium cross-couplings | es_ES |
dc.subject | Total synthesis | es_ES |
dc.title | Total Synthesis of Iso- and Bongkrekic Acids: Natural Antibiotics Displaying Potent Antiapoptotic Properties | es_ES |
dc.type | Artículo | es_ES |
dc.embargo.lift | 10000-01-01 | |
dc.embargo.terms | forever | es_ES |
dc.identifier.doi | 10.1002/chem.201002380 | |
dc.rights.accessRights | Cerrado | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química | es_ES |
dc.description.bibliographicCitation | Français, A.; Leyva Pérez, A.; Etxebarria-Jardi, G.; Peña, J.; Ley, SV. (2011). Total Synthesis of Iso- and Bongkrekic Acids: Natural Antibiotics Displaying Potent Antiapoptotic Properties. Chemistry - A European Journal. 17(1):329-343. doi:10.1002/chem.201002380 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | http://onlinelibrary.wiley.com/doi/10.1002/chem.201002380/pdf | es_ES |
dc.description.upvformatpinicio | 329 | es_ES |
dc.description.upvformatpfin | 343 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 17 | es_ES |
dc.description.issue | 1 | es_ES |
dc.relation.senia | 40585 |