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dc.contributor.author | Elena Fito, Santiago Fco | es_ES |
dc.contributor.author | Rodrigo Tarrega, Guillermo | es_ES |
dc.date.accessioned | 2016-10-11T09:48:28Z | |
dc.date.available | 2016-10-11T09:48:28Z | |
dc.date.issued | 2012-12 | |
dc.identifier.issn | 1879-6257 | |
dc.identifier.uri | http://hdl.handle.net/10251/71603 | |
dc.description.abstract | [EN] The application in recent years of network theory methods to the study of host-virus interactions is providing a new perspective to the way viruses manipulate the host to promote their own replication. An integrated molecular model of such pathosystems require three detailed maps describing, firstly, the interactions between viral elements, secondly, the interactions between host elements, and thirdly, the cross-interactions between viral and host elements. Here, we compile available information for Potyvirus infecting Arabidopsis thaliana. With an integrated model, it is possible to analyze the mode of virus action and how the perturbation of the virus targets propagates along the network. These studies suggest that viral pathogenicity results not only from the alteration of individual elements but it is a systemic property. | es_ES |
dc.description.sponsorship | This work was supported by the grant BFU2009-06993 from the Spanish Ministry of Science and Innovation to S.F.E. G.R. thanks an EMBO long-term fellowship co-funded by Marie Curie actions (ALTF-1177-2011). | |
dc.language | Inglés | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.ispartof | Current Opinion in Virology | es_ES |
dc.rights | Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) | es_ES |
dc.title | Towards an integrated molecular model of plant-virus interactions | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1016/j.coviro.2012.09.004 | |
dc.relation.projectID | info:eu-repo/grantAgreement/MICINN//BFU2009-06993/ES/Biologia Evolutiva Y De Sistemas De La Emergencia De Fitovirus De Rna/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC//ALTF-1177-2011/ | es_ES |
dc.rights.accessRights | Abierto | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes | es_ES |
dc.description.bibliographicCitation | Elena Fito, SF.; Rodrigo Tarrega, G. (2012). Towards an integrated molecular model of plant-virus interactions. Current Opinion in Virology. 2(6):719-724. https://doi.org/10.1016/j.coviro.2012.09.004 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | http://dx.doi.org/10.1016/j.coviro.2012.09.004 | es_ES |
dc.description.upvformatpinicio | 719 | es_ES |
dc.description.upvformatpfin | 724 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 2 | es_ES |
dc.description.issue | 6 | es_ES |
dc.relation.senia | 232219 | es_ES |
dc.identifier.pmid | 23017245 | |
dc.contributor.funder | Ministerio de Ciencia e Innovación | |
dc.contributor.funder | European Commission |