Harris, C. Jake; Scheibe, Marion; Wongpalee, Somsakul Pop; Liu, Wanlu; Cornett, Evan M.; Vaughan, Robert M.; Li, Xueqin; Chen, Wei; Xue, Yan; Zhong, Zhenhui; Yen, Linda; Barshop, William D.; Rayatpisheh, Shima; Gallego Bartolomé, Javier; Groth, Martin(American Association for the Advancement of Science (AAAS), 2018-12-07)
[EN] DNA methylation generally functions as a repressive transcriptional signal, but it is also known to activate gene expression. In either case, the downstream factors remain largely unknown. By using comparative ...
Wongpalee, Somsakul Pop; Liu, Shiheng; Gallego Bartolomé, Javier; Leitner, Alexander; Aebersold, Ruedi; Liu, Wanlu; Yen, Linda; Nohales, Maria A.; Kuo, Peggy Hsuanyu; Vashisht, Ajay A.; Wohlschlegel, James A.; Feng, Suhua; Kay, Steve A.; Zhou, Z. Hong; Jacobsen, Steven E.(Nature Publishing Group, 2019-09-02)
[EN]
Transcription by RNA polymerase V (Pol V) in plants is required for RNA-directed DNA methylation, leading to transcriptional gene silencing. Global chromatin association of Pol V requires components of the DDR complex ...
[EN] The ability to target epigenetic marks like DNA methylation to specific loci is important in both basic research and in crop plant engineering. However, heritability of targeted DNA methylation, how it impacts gene ...