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Browsing by Author "Martorell, Miguel"

Now showing items 1-5 of 5

A Gene Signature Combining the Tissue Expression of Three Angiogenic Factors is a Prognostic Marker in Early-stage Non-small Cell Lung Cancer

Sanmartín, Elena; Sirera Pérez, Rafael; Usó, Marta; Blasco, Ana; Gallach, Sandra; Figueroa, Santiago; Martínez, Nieves; Hernando, Cristina; Honguero, Antonio; Martorell, Miguel; Guijarro, Ricardo; Rosell, Rafael; Jantus-Lewintre, Eloisa; Camps, Carlos (Springer Verlag (Germany), 2014-02)

[EN] Background. Angiogenesis and lymphangiogenesis are key mechanisms for tumor growth and dissemination. They are mainly regulated by the vascular endothelial growth factor (VEGF) family of ligands and receptors. The aim ...
Analysis of the immune microenvironment in resected non-small cell lung cancer: the prognostic value of different T lymphocyte markers

Usó-Marco, Marta; Jantus-Lewintre, Eloisa; Bremnes, Roy M.; Calabuig-Fariñas, Silvia; Blasco-Cordellat, Ana; Pastor, Enrique; Borreda, Irene; Molina-Pinelo, Sonia; Paz-Ares, Luis; Guijarro, Ricardo; Martorell, Miguel; Forteza, Jerónimo; Camps-Herrero, Carlos; Sirera Pérez, Rafael (Impact Journals, LLC, 2016-08-16)

[EN] The prognosis of non-small cell lung cancer (NSCLC) remains poor and heterogeneous and new biomarkers are needed. As the immune system plays a pivotal role in cancer, the study of immune-related markers may provide ...
Analysis of the prognostic role of an immune checkpoint score in resected non-small cell lung cancer patients

Usó, Marta; Jantus-Lewintre, Eloisa; Calabuig-Farinas, Silvia; Blasco, Ana; Garcia del Olmo, Eva; Guijarro, Ricardo; Martorell, Miguel; Camps, Carlos; Sirera Pérez, Rafael (Taylor & Francis, 2017)

[EN] Tumors develop mechanisms to recruit tolerogenic immune cells and to induce the expression of molecules that act as immune checkpoints. This regulation of the immune microenvironment favors immune tolerance to the ...
Effect of clinical and histologic features on time to malignancy in 224 cases of oral leukoplakia treated by surgery

Bagan, José; Martorell, Miguel; Cebrián, Jose L.; Rubert, Andrea; Bagán, Leticia; Mezquida, Carlos; Hervás-Marín, David (Springer-Verlag, 2022-08)

[EN] Objectives Our main purpose and research question were to analyze and quantify whether there were signifcant diferences in the time to develop cancer among patients with oral leukoplakia (OL), comparing the more ...
MicroRNA profiling associated with non-small cell lung cancer: next generation sequencing detection, experimental validation, and prognostic value

Gallach-Garcia, Sandra; Jantus-Lewintre, Eloisa; Calabuig-Fariñas, Silvia; Montaner, David; Alonso, Sergio; Sirera Pérez, Rafael; Blasco, Ana; Usó-Marco, Marta; Guijarro, Ricardo; Martorell, Miguel; Camps-Herrero, Carlos (Impact Journals, LLC, 2017-06-22)

[EN] Background: The average five-year survival for non-small cell lung cancer (NSCLC) patients is approximately 15%. Emerging evidence indicates that microRNAs (miRNAs) constitute a new class of gene regulators in humans ...