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Mostrando ítems 1-20 de 95

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A copper switch for inducing CRISPR/Cas9-based transcriptional activation tightly regulates gene expression in Nicotiana benthamiana

García-Pérez, Elena; Diego-Martín, Borja; Quijano-Rubio, Alfredo; Moreno-Giménez, Elena; Selma, Sara; Orzáez Calatayud, Diego Vicente; Vázquez-Vilar, Marta (Springer (Biomed Central Ltd.), 2022-03-24)

[EN] Background CRISPR-based programmable transcriptional activators (PTAs) are used in plants for rewiring gene networks. Better tuning of their activity in a time and dose-dependent manner should allow precise control ...
A model of a rotating railway wheel for the prediction of sound radiation

Andrés-Ruiz, Víctor Tomás; Martínez Casas, José; Denia, F.D.; Thompson, D.J. (Elsevier, 2023-06-09)

[EN] The axial symmetry of a railway wheel is taken into account to expand its vibrational response around the circumferential direction using Fourier series. This allows the vibroacoustic problem of the wheel to be ...
A quantitative analysis of parametric CAD model complexity and its relationship to perceived modeling complexity

Contero, M.; Pérez Lopez, D.; Company, P.; Camba, J.D. (Elsevier, 2023-04)

[EN] Digital product data quality and reusability has been proven a critical aspect of the Model-Based Enterprise to enable the efficient design and redesign of products. The extent to which a history-based parametric CAD ...
A random spatio-temporal model for the dynamics of Candida Auris in Intensive Care Units with regular cleaning

Andreu-Vilarroig, Carlos; Cortés, J.-C.; Perez-Diukina, Cristina; Villanueva Micó, Rafael Jacinto (Elsevier, 2023-11-13)

[EN] Candida Auris is a pathogen that can express multiple virulence factors and is considered a significant menace to the Intensive Care Unit environment. In this work, we propose to model its growth with a computationally ...
A Reduced Order Model based on Artificial Neural Networks for nonlinear aeroelastic phenomena and application to composite material beams

Torregrosa, A. J.; Gil, A.; Quintero-Igeño, Pedro-Manuel; Cremades-Botella, Andrés (Elsevier, 2022-09-01)

[EN] Applications of composite materials in industry have increased due to their high stiffness-to-weight ratio. In the particular case of unidirectional fibers or perpendicular fabrics, the materials behavior is orthotropic, ...
Adaptability of invasive plants to climate change

González-Orenga, Sara; Boscaiu, Monica; Verdeguer Sancho, Mercedes María; Sánchez-Moreiras, A. M.; González, L; Vicente, Oscar (University of Agronomic Sciences and Veterinary Medicine of Bucharest, 2022-12)

[EN] Climate change represents one of the greatest environmental challenges of the 21st century, accentuated by deforestation and the degradation of habitats. Changes in vital aspects such as temperature, the amount and ...
Advancements in synthetic biology-based bacterial cancer therapy: A modular design approach

Arboleda-García, Andrés; Alarcon-Ruiz, Ivan; Boada-Acosta, Lissette; Boada-Acosta, Yadira Fernanda; Vignoni, Alejandro; Jantus-Lewintre, Eloisa (Elsevier, 2023-10)

[EN] Synthetic biology aims to program living bacteria cells with artificial genetic circuits for user-defined functions, transforming them into powerful tools with numerous applications in various fields, including oncology. ...
Agrobiodiversity: conservation, threats, challenges and strategies for the 21ST Century

Ruiz-González, Mario X.; Vicente, Oscar (University of Agronomic Sciences and Veterinary Medicine of Bucharest, 2023-01)

[EN] The conservation of agrobiodiversity begins by its characterisation to know it. On this knowledge, we must study the interactions of the different species with their abiotic and biotic context. However, as a consequence ...
An Exploratory Study on the Utility of Patient-Generated Health Data as a Tool for Health Care Professionals in Multiple Sclerosis Care

Guardado, Sharon; Mylonopoulou, Vasiliki; Rivera-Romero, Octavio; Patt, Nadine; Bansi, Jens; Giunti, Guido (Schattauer GmbH (Methods of Information in Medicine), 2023-12)

[EN] Background Patient-generated health data (PGHD) are data collected through technologies such as mobile devices and health apps. The integration of PGHD into health care workflows can support the care of chronic ...
Analysis of the consequences of a car to micromobility user side impact crashes

Pérez Zuriaga, Ana María; Dols Ruiz, Juan Francisco; Nespereira, Martín; García García, Alfredo; Sanjurjo-de-No, Almudena (Elsevier, 2023-12)

[EN] Introduction: The strong rise in modes of travel commonly referred to as micromobility has changed the mobility patterns and lifestyles in cities worldwide, especially after the COVID-19 pandemic. It has led to a ...
Analysis of the Current Status of Sensors and HBIM Integration: A Review Based on Bibliometric Analysis

Cornélio Vieira de Souza Rolim, Renan; López González, María Concepción; Viñals, Mª José (MDPI AG, 2024-04)

[EN] This article presents a bibliometric analysis conducted on the implementation of sensor extracted data in the context of Historical Building Information Modeling (HBIM) with a focus on the conservation of heritage ...
Annotation protocol and crowdsourcing multiple instance learning classification of skin histological images: The CR-AI4SkIN dataset

del Amor, Rocío; Pérez-Cano, Jose; López-Pérez, Miguel; Terradez, Liria; Aneiros-Fernandez, Jose; Morales, Sandra; Mateos, Javier; Molina, Rafael; Naranjo Ornedo, Valeriana (Elsevier, 2023-11)

[EN] Digital Pathology (DP) has experienced a significant growth in recent years and has become an essential tool for diagnosing and prognosis of tumors. The availability of Whole Slide Images (WSIs) and the implementation ...
Application of artificial neural networks to high-throughput synthesis of zeolites

Moliner Marin, Manuel; Serra, J. M.; Corma Canós, Avelino; Argente, Estefanía; Valero Cubas, Soledad; Botti, V. (Elsevier, 2005-02-04)

[EN] It is shown that multi-phase crystalline systems in zeolite synthesis can be modelled by using artificial neural networks (ANNs) and considering as input variables the molar compositions of the starting synthesis gel. ...
Aptamer-Capped Nanoporous Anodic Alumina for SARS-CoV-2 Spike Protein Detection

Caballos-Gómez, María Isabel; Aranda, María Nieves; López-Palacios, Alba; Pla, Luis; Santiago Felipe, Sara; Hernández-Montoto, Andy; Tormo-Mas, María Ángeles; Pemán, Javier; Gómez-Ruiz, María Dolores; Calbuig, Eva; Sánchez-Sendra, Beatriz; Francés-Gómez, Clara; Geller, Ron; Aznar, Elena; Martínez-Máñez, Ramón (Wiley-VCH Verlag GmbH & Co. KGaA, 2023-06)

[EN] The COVID-19 pandemic, which began in 2019, has highlighted the importance of testing and tracking infected individuals as a means of mitigating the spread of the virus. In this context, the development of sensitive ...
BDNF-Gene Transfected Schwann Cell-Assisted Axonal Extension and Sprouting on New PLA-PPy Microfiber Substrates

Gisbert-Roca, Fernando; André, Franck M.; Más Estellés, Jorge; Monleón Pradas, Manuel; Mir, Lluis M.; Martínez-Ramos, Cristina (John Wiley & Sons, 2021-05)

[EN] The work here reported analyzes the effect of increased efficiency of brainderived neurotrophic factor (BDNF) production by electroporated Schwann cells (SCs) on the axonal extension in a coculture system on a biomaterial ...
Characterization and Comparison of WO3/WO3-MoO3 and TiO2/TiO2-ZnO Nanostructures for Photoelectrocatalytic Degradation of the Pesticide Imazalil

Cifre-Herrando, Mireia; Roselló-Márquez, Gemma; Navarro Gázquez, Pedro José; Muñoz-Portero, María-José; Blasco-Tamarit, E.; Garcia-Anton, Jose (MDPI AG, 2023-09)

[EN] Tungsten oxide (WO3) and zinc oxide (ZnO) are n-type semiconductors with numerous applications in photocatalysis. The objective of this study was to synthesize and characterize different types of nanostructures (WO3, ...
Characterization of Arabidopsis Post-Glycosylphosphatidylinositol Attachment to Proteins Phospholipase 3 Like Genes

Bernat-Silvestre, Cesar; Ma, Yingxuan; Johnson, Kim; Ferrando Monleón, Alejandro Ramón; Aniento, Fernando; Marcote, María Jesús (Frontiers Media SA, 2022-02-11)

[EN] Lipid remodeling of Glycosylphosphatidylinositol (GPI) anchors is required for their maturation and may influence the localization and function of GPI-anchored proteins (GPI-APs). Maturation of GPI-anchors is well ...
Comparative Analysis of Chromatin-Delivered Biomarkers in the Monitoring of Sepsis and Septic Shock: A Pilot Study

Beltrán-García, Jesús; Manclus Ciscar, Juan José; García-López, Eva M.; Carbonell, Nieves; Ferreres, José; Rodríguez-Gimillo, María; Garcés, Concepción; Pallardó, Federico V.; García-Giménez, José L.; Montoya, Ángel; Romá-Mateo, Carlos (MDPI AG, 2021-09)

[EN] Sepsis management remains one of the most important challenges in modern clinical practice. Rapid progression from sepsis to septic shock is practically unpredictable, hence the critical need for sepsis biomarkers ...
Comparative analysis of the European Regulatory Framework for C&D Waste Management

Colmenero-Fonseca, Fabiola; Cárcel-Carrasco, Javier; Preciado, Adolfo; Martínez-Corral, Aurora-María; Salas Montoya, Andrés (Hindawi Limited, 2023-12-14)
Comparison of the Stability and Accuracy of Deterministic Project Cost Prediction Methods in Earned Value Management

Barrientos-Orellana, Alexis; Ballesteros-Pérez, Pablo; Mora-Meliá, Daniel; Cerezo-Narváez, Alberto; Gutiérrez-Bahamondes, Jimmy H. (MDPI AG, 2023-05-02)

[EN] Completing a project on time and on budget are essential factors for the success of any project. One technique that allows predicting the final cost of a project is earned value management (EVM). In this technique, ...