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Mostrando ítems 1-9 de 9

AssemblyNet: A large ensemble of CNNs for 3D whole brain MRI segmentation

Coupé, Pierrick; Mansencal, Boris; Clement, Michael; Giraud, Rémi; Denis de Senneville, Baudouin; Ta, Vinh-Thong; Lepetit, Vincent; Manjón Herrera, José Vicente (Elsevier, 2020-10-01)

[EN] Whole brain segmentation of fine-grained structures using deep learning (DL) is a very challenging task since the number of anatomical labels is very high compared to the number of available training images. To address ...
Characterization of molecular mechanisms underlying the axonal Charcot-Marie-Tooth neuropathy caused by MORC2 mutations

Sancho, Paula; Bartesaghi, Luca; Miossec, Olivia; García-García, Francisco; Ramírez-Jiménez, Laura; Siddell, Anna; Ajkesson, Elisabet; Hedlund, Eva; Lassuthova, Petra; Pascual-Pascual, Samuel I.; Sevilla, Teresa; Kennerson, Marina; Lupo, Vincenzo; Chrast, Roman; Espinós-Armero, Carmen Ángeles (Oxford University Press, 2019-05-15)

[EN] Mutations in MORC2 lead to an axonal form of Charcot-Marie-Tooth (CMT) neuropathy type 2Z. To date, 31 families have been described with mutations in MORC2, indicating that this gene is frequently involved in axonal ...
Hippocampal-amygdalo-ventricular atrophy score: Alzheimer disease detection using normative and pathological lifespan models

Coupé, Pierrick; Manjón Herrera, José Vicente; Mansencal, Boris; Tourdias, Thomas; Catheline, Gwenaelle; Planche, Vincent (John Wiley & Sons, 2022-07)

[EN] In this article, we present an innovative MRI-based method for Alzheimer disease (AD) detection and mild cognitive impairment (MCI) prognostic, using lifespan trajectories of brain structures. After a full screening ...
ICT-based system to predict and prevent falls (iStoppFalls): study protocol for an international multicenter randomized controlled trial

Gschwind, Yves J.; Eichberg, Sabine; Marston, Hannah R.; Ejupi, Andreas; De Rosario Martínez, Helios; Kroll, Michael; Drobics, Mario; Annegarn, Janneke; Wieching, Rainer; Lord, Stephen R.; Aal, Konstantin; Delbaere, Kim (BioMed Central, 2014-08-20)

[EN] Background: Falls are very common, especially in adults aged 65 years and older. Within the current international European Commission's Seventh Framework Program (FP7) project 'iStoppFalls' an Information and Communication ...
ICT-based system to predict and preventfalls (iStoppFalls): results from aninternational multicenter randomizedcontrolled trial

Gschwind, Yves J.; Eichberg, Sabine; Ejupi, Andreas; De Rosario Martínez, Helios; Kroll, Michael; Marston, Hannah R.; Drobics, Mario; Annegarn, Janneke; Wieching, Rainer; Lord, Stephen R.; Aal, Konstantin; Vaziri, Daryoush; Woodbury, Ashley; Fink, Dennis; Delbaere, Kim (Springer Verlag (Germany), 2015-11-27)

[EN] Background: Falls and fall-related injuries are a serious public health issue. Exercise programs can effectively reduce fall risk in older people. The iStoppFalls project developed an Information and Communication ...
Lifespan Changes of the Human Brain In Alzheimer's Disease

Coupé, Pierrick; Manjón Herrera, José Vicente; Lanuza, Enrique; Catheline, Gwenaelle (Nature Publishing Group, 2019-03-08)

[EN] Brain imaging studies have shown that slow and progressive cerebral atrophy characterized the development of Alzheimer's Disease (AD). Despite a large number of studies dedicated to AD, key questions about the lifespan ...
Technology use, adoption and behavior in older adults: Results from the iStoppFalls project

Marston, Hannah R.; Kroll, Michael; Fink, Dennis; De Rosario Martínez, Helios; Gschwind, Yves J. (Taylor & Francis (Routledge), 2016)

[EN] Technology use is a common constituent of modern life. However, little is known about older adults' use of technology. This article presents a subset of data collected via the technology deployed in the iStoppFalls ...
The My Active and Healthy Aging (My-AHA) ICT platform to detect and prevent frailty in older adults: Randomized control trial design and protocol

Summers, Mathew J.; Rainero, Innocenzo; Vercelli, Alessandro E.; Aumayr, Georg Aumayr; De Rosario Martínez, Helios; Mönter, Michaela; Kawashima, Ryuta (Elsevier, 2018-07-09)

[EN] Introduction Frailty increases the risk of poor health outcomes, disability, hospitalization, and death in older adults and affects 7%¿12% of the aging population. Secondary impacts of frailty on psychological health ...
Towards a Unified Analysis of Brain Maturation and Aging across the Entire Lifespan: A MRI Analysis

Coupé, Pierrick; Catheline, Gwenaelle; Lanuza, Enrique; Manjón Herrera, José Vicente (John Wiley & Sons, 2017-11)

[EN] There is no consensus in literature about lifespan brain maturation and senescence, mainly because previous lifespan studies have been performed on restricted age periods and/or with a limited number of scans, making ...