Microwave-assisted synthesis and spectroscopic properties of novel pyridine-based fluorescent molecular probes

Handle

https://riunet.upv.es/handle/10251/130170

Cita bibliográfica

Fiedor, P.; Ortyl, J.; Galek, M. (2019). Microwave-assisted synthesis and spectroscopic properties of novel pyridine-based fluorescent molecular probes. Editorial Universitat Politècnica de València. 394-400. https://doi.org/10.4995/AMPERE2019.2019.9829

Titulación

Resumen

[EN] Fluorescent molecular probes become interesting analytical tools in determination and labeling of chemical compounds and physical properties such as viscosity and polarity. Currently known fluorescent molecular probes can selectively and regardless of the environment detect only few molecules, and applicability in determination of micro- viscosity and micro-polarity are limited to narrow range and specific condition, therefore design and synthesis of novel molecular probes with extended range of operation are highly needed [1]. Traditional synthesis of 2-amino-4,6-diphenyl-pyridine-3-carbonitrile’s requires two step reaction with long heating time or and toxic solvent. By application of microwave irradiation, reaction time can be firmly shortened with the same or higher efficiency [2]. Derivatives of 2-amino-4,6-diphenyl-pyridine-3-carbonitrile can find application in different fields of science. Depending on the structure of fluorophore, those compounds exhibit high sensitivity to changes in polarity and viscosity of environment, also concentration of specific cations, and pH can be determined by measuring of fluorescence spectrum.

Fuente

AMPERE 2019. 17th International Conference on Microwave and High Frequency Heating. isbn: 9788490487198

Editorial

Editorial Universitat Politècnica de València

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