Patterns of calcium channel (TRPV6) expression in rabbit gut epithelium

dc.contributor.authorRanjan, Rajeshes_ES
dc.contributor.authorDas, Parthaes_ES
dc.contributor.authorBatabyal, Subhashishes_ES
dc.contributor.authorMinj, Arpana Priyankaes_ES
dc.date.accessioned2021-01-27T10:04:08Z
dc.date.available2021-01-27T10:04:08Z
dc.date.issued2020-12-30
dc.description.abstract[EN] The present study was undertaken to explore the immunohistochemical localisation of TRPV6 calcium channels in rabbit gut epithelium that are actively involved in calcium absorption. To undertake the research, twelve apparently healthy adult female rabbits with a body weight between 1.0 to 1.5 kg were procured, acclimatised and divided into two groups: control and test. Both groups were kept on same feed along with exogenous calcium supplementation in test group animals only. The serum calcium level revealed that normally a high value of serum calcium is maintained in the rabbit as compared to other mammals, thus indicating that the homeostatic mechanism might be poorly developed. Immunohistochemistry and reverse transcription polymerase chain reaction analysis revealed that the caecum was the site of maximum calcium absorption in rabbit, followed by the duodenum and jejunum. The expression pattern of TRPV6 protein/mRNA was weaker in test group animals than in the control group, indicating that the channel was functional in low calcium concentration in the gut.en_EN
dc.description.accrualMethodOJSes_ES
dc.description.bibliographicCitationRanjan, R.; Das, P.; Batabyal, S.; Minj, AP. (2020). Patterns of calcium channel (TRPV6) expression in rabbit gut epithelium. World Rabbit Science. 28(4):187-197. https://doi.org/10.4995/wrs.2020.12161es_ES
dc.description.issue4es_ES
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dc.description.sponsorshipWest Bengal University of Animal and Fishery Scienceses_ES
dc.description.upvformatpfin197es_ES
dc.description.upvformatpinicio187es_ES
dc.description.volume28es_ES
dc.identifier.doi10.4995/wrs.2020.12161
dc.identifier.eissn1989-8886
dc.identifier.issn1257-5011
dc.identifier.urihttps://riunet.upv.es/handle/10251/160027
dc.languageIngléses_ES
dc.publisherUniversitat Politècnica de Valènciaes_ES
dc.relation.ispartofWorld Rabbit Sciencees_ES
dc.relation.pasarelaOJS\12161es_ES
dc.relation.publisherversionhttps://doi.org/10.4995/wrs.2020.12161es_ES
dc.relation.references10.1210/endo-84-4-926es_ES
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dc.relation.references10.1016/j.pep.2011.05.021es_ES
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dc.relation.references10.1152/ajpgi.00036.2003es_ES
dc.relation.references10.1016/j.tvjl.2008.06.020es_ES
dc.rightsReconocimiento - No comercial - Compartir igual (by-nc-sa)es_ES
dc.rights.accessRightsAbiertoes_ES
dc.subjectRabbites_ES
dc.subjectGut epitheliumes_ES
dc.subjectTRPV6es_ES
dc.subjectImmunohistochemistryes_ES
dc.subjectRT-PCRes_ES
dc.titlePatterns of calcium channel (TRPV6) expression in rabbit gut epitheliumes_ES
dc.typeArtículoes_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
dspace.entity.typePublication
upv.uuidd83e8610-2bc2-4a68-bbd0-aaf852fe1b15es_ES

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