Changes of oxidant-antioxidant parameters in small intestines from rabbits infected with E. intestinalis and E. magna

dc.contributor.authorZhou, Yun Xiaoes_ES
dc.contributor.authorYuan, Xues_ES
dc.contributor.authorHu, Xiao Fenes_ES
dc.contributor.authorYang, Shan Shanes_ES
dc.contributor.authorZhong, Sheng Weies_ES
dc.contributor.authorYang, Ting Yues_ES
dc.contributor.authorZhao, Guo Tonges_ES
dc.contributor.authorJiang, Yi Jiees_ES
dc.contributor.authorLi, Yonges_ES
dc.contributor.funderNational Natural Science Foundation of Chinaes_ES
dc.contributor.funderNatural Science Foundation of Jiangxi Provincees_ES
dc.date.accessioned2023-01-11T11:14:07Z
dc.date.available2023-01-11T11:14:07Z
dc.date.issued2022-12-29
dc.description.abstract[EN] Rabbit coccidiosis is a very serious disease caused by protozoan parasites of the genus Eimeria, which increases the production rate of free radicals, especially reactive oxygen species. When the generation of free radicals exceeds the scavenging capacity of the body s antioxidant system, the oxidant-antioxidant balance is broken, resulting in oxidative stress. This study was designed to investigate the effect on the oxidant-antioxidant status of rabbits infected with E. intestinalis and E. magna. To this end, eighteen 30-d-old weaned rabbits were randomly allocated into three groups as follows: the E. intestinalis infection group with 3×103 sporulated oocysts of E. intestinalis, the E. magna infection group with 20×103 sporulated oocysts of E. magna, and the uninfected control group. We measured the activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) and total antioxidant capacity (T-AOC) and the contents of malondialdehyde (MDA) in rabbits small intestinal tissues (duodenum, jejunum and ileum) of the three groupson day 8. The results showed that CAT activity and MDA levels significantly increased, while the activities of SOD, GSH-Px and T-AOC decreased after E. intestinalis and E. magna infection. Besides, the jejunum and ileum were particularly damaged in the rabbits. It is concluded that the pathological oxidative stress occurs during the E. intestinalis and E. magna infection process and the body s oxidant-antioxidant balance is disrupted.en_EN
dc.description.accrualMethodOJSes_ES
dc.description.bibliographicCitationZhou, YX.; Yuan, X.; Hu, XF.; Yang, SS.; Zhong, SW.; Yang, TY.; Zhao, GT.... (2022). Changes of oxidant-antioxidant parameters in small intestines from rabbits infected with E. intestinalis and E. magna. World Rabbit Science. 30(4):287-293. https://doi.org/10.4995/wrs.2022.17395es_ES
dc.description.issue4es_ES
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dc.description.sponsorshipThis experiment was supported by the National Natural Science Foundation Project of China (nos. 31960688 and 31360592) and the Natural Science Foundation Project of Jiangxi Province (no. 20181BAB204016).es_ES
dc.description.upvformatpfin293es_ES
dc.description.upvformatpinicio287es_ES
dc.description.volume30es_ES
dc.identifier.doi10.4995/wrs.2022.17395
dc.identifier.eissn1989-8886
dc.identifier.issn1257-5011
dc.identifier.urihttps://riunet.upv.es/handle/10251/191227
dc.languageIngléses_ES
dc.publisherUniversitat Politècnica de Valènciaes_ES
dc.relation.ispartofWorld Rabbit Sciencees_ES
dc.relation.pasarelaOJS\17395es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/NSFC//31960688es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/NSFC//31360592es_ES
dc.relation.projectIDinfo:eu-repo/grantAgreement/Natural Science Foundation of Jiangxi Province//20181BAB204016es_ES
dc.relation.publisherversionhttps://doi.org/10.4995/wrs.2022.17395es_ES
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dc.rightsReconocimiento - No comercial - Compartir igual (by-nc-sa)es_ES
dc.rights.accessRightsAbiertoes_ES
dc.subjectE. magnaes_ES
dc.subjectE. intestinalises_ES
dc.subjectOxidative stresses_ES
dc.subjectOxidant-antioxidant balancees_ES
dc.subjectRabbites_ES
dc.titleChanges of oxidant-antioxidant parameters in small intestines from rabbits infected with E. intestinalis and E. magnaes_ES
dc.typeArtículoes_ES
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_ES
dspace.entity.typePublication
upv.uuidefedddbf-4281-419b-9152-ccf866c97dd0es_ES

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