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Cytotoxic effect of 4-hydroxytamoxifen conjugate material on human Schwann cells: Synthesis and characterization

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Cytotoxic effect of 4-hydroxytamoxifen conjugate material on human Schwann cells: Synthesis and characterization

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Escobar Ivirico, JL.; Beaumont, M.; García Cruz, DM.; Gómez Pinedo, U.; Monleón Pradas, M. (2013). Cytotoxic effect of 4-hydroxytamoxifen conjugate material on human Schwann cells: Synthesis and characterization. Journal of Bioactive and Compatible Polymers. 28(6):574-589. https://doi.org/10.1177/0883911513506664

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/100708

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Title: Cytotoxic effect of 4-hydroxytamoxifen conjugate material on human Schwann cells: Synthesis and characterization
Author: Escobar Ivirico, Jorge Luis Beaumont, Marco García Cruz, Dunia Mercedes Gómez Pinedo, Ulises Monleón Pradas, Manuel
UPV Unit: Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada
Issued date:
Abstract:
[EN] In this study, the toxicity of 4-hydroxytamoxifen (4-OHT) on human Schwann cells (HSCs) was evaluated. Substantial alterations in the cell morphology and viability were observed at 4-OHT concentrations higher than 3 ...[+]
Subjects: 4-Hydroxytamoxifen , Cytotoxicity , Estrogen receptor delivery , Human Schwann cells , Drug-polymer conjugate
Copyrigths: Cerrado
Source:
Journal of Bioactive and Compatible Polymers. (issn: 0883-9115 )
DOI: 10.1177/0883911513506664
Publisher:
SAGE Publications
Publisher version: https://doi.org/10.1177/0883911513506664
Project ID:
info:eu-repo/grantAgreement/MICINN//MAT2011-28791-C03-02/ES/MATERIALES DE SOPORTE Y LIBERACION CONTROLADA PARA LA REGENERACION DE ESTRUCTURAS NEURALES AFECTADAS POR ICTUS/
info:eu-repo/grantAgreement/MICINN//PRI-PIMNEU-2011-1372/ES/MATERIALES BIFUNCIONALES PARA LA REGENERACION NEURAL DE AREAS AFECTADAS POR ICTUS/
Thanks:
This study was financially supported by the Spanish Science & Innovation Ministry through MAT 2011-28791-C03 and PRI-PIMNEU-2011-1372 (ERA-NET call) projects.
Type: Artículo

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