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Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol-Ene or Thiol-Yne Coupling Chemistry

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Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol-Ene or Thiol-Yne Coupling Chemistry

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Bañuls Polo, M.; Jimenez-Meneses, P.; Meyer, A.; Vasseur, J.; Morvan, F.; Escorihuela Fuentes, J.; Puchades, R.... (2017). Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol-Ene or Thiol-Yne Coupling Chemistry. Bioconjugate Chemistry. 28(2):496-506. https://doi.org/10.1021/acs.bioconjchem.6b00624

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/102305

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Title: Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol-Ene or Thiol-Yne Coupling Chemistry
Author: Bañuls Polo, María-José Jimenez-Meneses, P. Meyer, A. Vasseur, J.J. Morvan, F. Escorihuela Fuentes, Jorge Puchades, Rosa Maquieira Catala, Ángel
UPV Unit: Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada
Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
[EN] Nucleic acid microarray-based assay technology has shown lacks in reproducibility, reliability, and analytical sensitivity. Here, a new strategy of probe attachment modes for silicon-based materials is built up. Thus, ...[+]
Copyrigths: Reserva de todos los derechos
Source:
Bioconjugate Chemistry. (issn: 1043-1802 )
DOI: 10.1021/acs.bioconjchem.6b00624
Publisher:
American Chemical Society
Publisher version: https://doi.org/10.1021/acs.bioconjchem.6b00624
Project ID:
info:eu-repo/grantAgreement/EC/H2020/644242/EU/Self-amplified photonic biosensing platform for microRNA-based early diagnosis of diseases/
info:eu-repo/grantAgreement/MINECO//CTQ2013-45875-R/ES/BIOSENSADO EN SOPORTES INTERACTIVOS CON PROPIEDADES INTERFEROMETRICAS PARA APLICACIONES CLINICAS. DEMOSTRACION EN FARMACOGENETICA Y ALERGIAS MEDICAMENTOSAS/
GV/PROMETEOII/2014/040
CEE/644242
Thanks:
The authors thank Dr. Elena Pinilla for her helpful discussion about AFM results. This work was funded by EU’s program Horizon 2020 ICT-26-2014-644242, Spanish Ministry MINECO CTQ/2013/45875-R FEDER, and local administration ...[+]
Type: Artículo

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