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CHANGES IN PLASMA PROGESTERONE AND ESTRADIOL DURING NATURAL PROSTAGLANDIN F2a-INDUCED PARTURITION IN THE RABBIT.

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CHANGES IN PLASMA PROGESTERONE AND ESTRADIOL DURING NATURAL PROSTAGLANDIN F2a-INDUCED PARTURITION IN THE RABBIT.

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dc.contributor.author Rebollar, P.G.
dc.contributor.author Alvariño, J.M.R.
dc.contributor.author Illera, J.C.
dc.contributor.author Silvan, C.
dc.contributor.author Lorenzo, P.
dc.date.accessioned 2011-03-21T09:50:00Z
dc.date.available 2011-03-21T09:50:00Z
dc.date.issued 1997
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/10432
dc.description.abstract [EN] The influence of administration of natural prostaglandin F2a (PgF) on plasma progesterone (P4) and estradiol-17(l (E2) levels during the last days of pregnancy (days 29-32) was studied in 13 doe rabbits of the California x New Zealand White breed. Animals were allocated to receive either a single intramuscular injection of 800 or 1200μg of natural PgF on day 29 of pregnancy at 10 h (treated groups) or no injection (control group). AH does treated with PgF kindled within 60 h after injection, whereas the variation in birth time in control group was greater (79.2 ± 8.9 h). No influence of the prostaglandin treatment on mean plasma estradiol (5.2 pg/ml) and both litter size and born dead (7.2 ± 0.7 and 0.4 ± 0.6, respectively) was observed. A significant fall in progesterone concentration was defected in treated animals at 20 h on day 29 compared with control group (3.17 ± 0.22 and 3.47 ± 0.32 vs. 6.7 ± 1.4 ng/ml; P<0.05). Our results suggest that the induction of parturition with natural PgF has similar effects on plasma P4 levels and in synchronization of parturitions to synthetic analogues, although the dose administered is greater. es_ES
dc.description.abstract [FR] L'inf/uence de f'administration de prostag/andine naturel/e F2a (PgF) sur le taux de progestérone (P4) et d'estradiol-17b (E2) plasmatique durant les demiers jours de la gestatlon (29-32 jours) a été étudié sur 13 tapines de race Calífomien x NZW Les animaux ont été répartis en trois lots, deux recevant une seule injection intramusculaire de 800 ou 1200 μg de PgF naturel/e, él 1 O heures, au 29eme jour de gestation, l'autre ne recevant aucune injection (lot contr61e). Toutes les lapines traitées avec PgF ont mis bas enviran 60 heures aprés l'injection, tandis que pour ce/les du groupe contr61e le moment de la mise bas a été plus variable: 79,2 ± 8,9 heures. Le traitement par la prostaglandine n'a pas eu d'influence sur le taux mayen d'CBstradiol plasmatique (5,2 pglml) ni sur la taille de la portée ou le nombre de mort-nés (7,2 ± O, 7 et 0.4 ± 0,6, respectivement). une chute significative de la concentration en progestérone, par rapport au groupe controle, a été observée chez les animaux traités él 20 heures au 29eme jour (3, 17 ±0,22 et 3.47 ± 0,32 vs 6,7 ± 1,4 ng/ml, P<0,05). Nos résultats suggerent que l'induction de la mise bas avec PgF naturel/e a des effets sur les taux de P 4 plasmatique et sur la synchronisation des mises-bas similaires él ceux de la mame molécule synthétique, bien que la dose administrée soit supérieure.
dc.language Inglés es_ES
dc.publisher World Rabbit Science. ICTA. UPV es_ES
dc.relation.ispartof World Rabbit Science
dc.rights Reconocimiento - No comercial (by-nc) es_ES
dc.title CHANGES IN PLASMA PROGESTERONE AND ESTRADIOL DURING NATURAL PROSTAGLANDIN F2a-INDUCED PARTURITION IN THE RABBIT. es_ES
dc.type Artículo es_ES
dc.date.updated 2011-03-21T09:45:12Z
dc.identifier.doi 10.4995/wrs.1997.312 es_ES
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Rebollar, P.; Alvariño, J.; Illera, J.; Silvan, C.; Lorenzo, P. (1997). CHANGES IN PLASMA PROGESTERONE AND ESTRADIOL DURING NATURAL PROSTAGLANDIN F2a-INDUCED PARTURITION IN THE RABBIT. World Rabbit Science. doi:10.4995/wrs.1997.312 es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.1997.312 es_ES
dc.description.volume 05
dc.description.issue 1
dc.identifier.eissn 1989-8886 es_ES


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