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Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions

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Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions

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dc.contributor.author Rodríguez Ortega, Alejandro es_ES
dc.contributor.author Tembl, Jose es_ES
dc.contributor.author Mesa Gresa, Patricia es_ES
dc.contributor.author Muñoz, Miguel Angel es_ES
dc.contributor.author Montoya, Pedro es_ES
dc.contributor.author Rey, Beatriz es_ES
dc.date.accessioned 2018-09-25T07:13:01Z
dc.date.available 2018-09-25T07:13:01Z
dc.date.issued 2017 es_ES
dc.identifier.issn 1932-6203 es_ES
dc.identifier.uri http://hdl.handle.net/10251/108064
dc.description.abstract [EN] The aim of this study is to characterize in resting-state conditions the cerebral blood flow velocity (CBFV) signals of fibromyalgia patients. The anterior and middle cerebral arteries of both hemispheres from 15 women with fibromyalgia and 15 healthy women were monitored using Transcranial Doppler (TCD) during a 5-minute eyes-closed resting period. Several signal processing methods based on time, information theory, frequency and time-frequency analyses were used in order to extract different features to characterize the CBFV signals in the different vessels. Main results indicated that, in comparison with control subjects, fibromyalgia patients showed a higher complexity of the envelope CBFV and a different distribution of the power spectral density. In addition, it has been observed that complexity and spectral features show correlations with clinical pain parameters and emotional factors. The characterization features were used in a lineal model to discriminate between fibromyalgia patients and healthy controls, providing a high accuracy. These findings indicate that CBFV signals, specifically their complexity and spectral characteristics, contain information that may be relevant for the assessment of fibromyalgia patients in resting-state conditions. es_ES
dc.language Inglés es_ES
dc.publisher Public Library of Science es_ES
dc.relation MINECO/PSI2013-48260-C3-2-R es_ES
dc.relation.ispartof PLoS ONE es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject.classification EXPRESION GRAFICA EN LA INGENIERIA es_ES
dc.title Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1371/journal.pone.0180253 es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Gráfica - Departament d'Enginyeria Gràfica es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Interuniversitario de Investigación en Bioingeniería y Tecnología Orientada al Ser Humano - Institut Interuniversitari d'Investigació en Bioenginyeria i Tecnologia Orientada a l'Ésser Humà es_ES
dc.description.bibliographicCitation Rodriguez Ortega, A.; Tembl, J.; Mesa Gresa, P.; Muñoz, MA.; Montoya, P.; Rey, B. (2017). Altered cerebral blood flow velocity features in fibromyalgia patients in resting-state conditions. PLoS ONE. 12(7):e0180253 (1)-e0180253 (21). doi:10.1371/journal.pone.0180253 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1371/journal.pone.0180253 es_ES
dc.description.upvformatpinicio e0180253 (1) es_ES
dc.description.upvformatpfin e0180253 (21) es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 12 es_ES
dc.description.issue 7 es_ES
dc.identifier.pmid 28700720 en_EN
dc.identifier.pmcid PMC5507513 en_EN
dc.relation.pasarela 343767 es_ES
dc.contributor.funder MINISTERIO DE ECONOMIA INDUSTRIA Y COMPETITIVIDAD es_ES


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