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Sensitivity analysis revealing the effect of modulating ionic mechanisms on calcium dynamics in simulated human heart failure

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Sensitivity analysis revealing the effect of modulating ionic mechanisms on calcium dynamics in simulated human heart failure

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Mora Fenoll, MT.; Ferrero De Loma-Osorio, JM.; Romero Pérez, L.; Trénor Gomis, BA. (2017). Sensitivity analysis revealing the effect of modulating ionic mechanisms on calcium dynamics in simulated human heart failure. PLoS ONE. 12(11):1-19. https://doi.org/10.1371/journal.pone.0187739

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Title: Sensitivity analysis revealing the effect of modulating ionic mechanisms on calcium dynamics in simulated human heart failure
Author: Mora Fenoll, María Teresa Ferrero De Loma-Osorio, José María Romero Pérez, Lucia Trénor Gomis, Beatriz Ana
UPV Unit: Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica
Issued date:
Abstract:
[EN] Abnormal intracellular Ca2+ handling is the major contributor to the depressed cardiac contractility observed in heart failure. The electrophysiological remodeling associated with this pathology alters both the action ...[+]
Copyrigths: Reconocimiento (by)
Source:
PLoS ONE. (issn: 1932-6203 )
DOI: 10.1371/journal.pone.0187739
Publisher:
Public Library of Science
Publisher version: https://doi.org/10.1371/journal.pone.0187739
Project ID:
AEI/DPI2016-75799-R
info:eu-repo/grantAgreement/MINECO//DPI2015-69125-R/ES/SIMULACION COMPUTACIONAL PARA LA PREDICCION PERSONALIZADA DE LOS EFECTOS DE LOS FARMACOS SOBRE LA ACTIVIDAD CARDIACA/
Thanks:
This work was partially supported by the "Plan Estatal de Investigacion Cientifica y Tecnica y de Innovacion 2013-2016" from the Ministerio de Economia, lndustria y Competitividad of Spain and Fondo Europeo de Desarrollo ...[+]
Type: Artículo

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