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Current Bioengineering and Regenerative Strategies for the Generation of Kidney Grafts on Demand

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Current Bioengineering and Regenerative Strategies for the Generation of Kidney Grafts on Demand

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dc.contributor.author Garcia-Dominguez, X. es_ES
dc.contributor.author Vicente Antón, José Salvador es_ES
dc.contributor.author Vera Donoso, Cesar David es_ES
dc.contributor.author Marco-Jiménez, Francisco es_ES
dc.date.accessioned 2018-11-09T05:34:38Z
dc.date.available 2018-11-09T05:34:38Z
dc.date.issued 2017 es_ES
dc.identifier.issn 1527-2737 es_ES
dc.identifier.uri http://hdl.handle.net/10251/112165
dc.description.abstract [EN] Currently in the USA, one name is added to the organ transplant waiting list every 15 min. As this list grows rapidly, fewer than one-third of waiting patients can receive matched organs from donors. Unfortunately, many patients who require a transplant have to wait for long periods of time, and many of them die before receiving the desired organ. In the USA alone, over 100,000 patients are waiting for a kidney transplant. However, it is a problem that affects around 6% of the word population. Therefore, seeking alternative solutions to this problem is an urgent work. Here, we review the current promising regenerative technologies for kidney function replacement. Despite many approaches being applied in the different ways outlined in this work, obtaining an organ capable of performing complex functions such as osmoregulation, excretion or hormone synthesis is still a long-term goal. However, in the future, the efforts in these areas may eliminate the long waiting list for kidney transplants, providing a definitive solution for patients with end-stage renal disease. es_ES
dc.description.sponsorship This study was supported by a grant from ALCER-TURIA, ASTELLAS and PRECIPITA CROWDFUNDING.
dc.language Inglés es_ES
dc.publisher Springer-Verlag es_ES
dc.relation.ispartof Current Urology Reports es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Kidney disease es_ES
dc.subject Kidney engineering es_ES
dc.subject Blastocyst complementation es_ES
dc.subject Stem cells es_ES
dc.subject Kidney regeneration es_ES
dc.subject Decellularization es_ES
dc.subject.classification PRODUCCION ANIMAL es_ES
dc.subject.classification BIOLOGIA ANIMAL es_ES
dc.title Current Bioengineering and Regenerative Strategies for the Generation of Kidney Grafts on Demand es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1007/s11934-017-0650-6 es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal es_ES
dc.description.bibliographicCitation Garcia-Dominguez, X.; Vicente Antón, JS.; Vera Donoso, CD.; Marco-Jiménez, F. (2017). Current Bioengineering and Regenerative Strategies for the Generation of Kidney Grafts on Demand. Current Urology Reports. 18(1):1-8. https://doi.org/10.1007/s11934-017-0650-6 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://doi.org/10.1007/s11934-017-0650-6 es_ES
dc.description.upvformatpinicio 1 es_ES
dc.description.upvformatpfin 8 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 18 es_ES
dc.description.issue 1 es_ES
dc.identifier.pmid 28092070
dc.relation.pasarela S\324349 es_ES
dc.contributor.funder Asociación para la lucha contra las enfermedades del riñón
dc.contributor.funder Astellas Pharma
dc.contributor.funder Fundación Española para la Ciencia y la Tecnología
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