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Molecular features of hepatitis E virus from farmed rabbits in Shandong province, China

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Molecular features of hepatitis E virus from farmed rabbits in Shandong province, China

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dc.contributor.author Zhang, Hongna es_ES
dc.contributor.author Zhou, Yufa es_ES
dc.contributor.author Liu, Jingbo es_ES
dc.date.accessioned 2019-01-03T11:20:18Z
dc.date.available 2019-01-03T11:20:18Z
dc.date.issued 2018-12-27
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/114677
dc.description.abstract [EN] This study was undertaken to investigate the genetic variability of hepatitis E virus (HEV) from farmed rabbits in Shandong province, China. A total of 50 fresh faecal samples from 5 rabbit farms were collected and subjected to reverse transcription and nested polymerase chain reaction (RT-nPCR) for a fragment sequence of HEV capsid gene. The results demonstrated that HEV RNA was observed in 6 faecal samples (6/50, 12.0%). In addition, the result of phylogenetic analysis showed that the 6 HEV isolates were classified into HEV-3 genotype with other rabbit HEV isolates from other countries, and shared 85.2-87.2%, 81.5-83.1%, and 77.0-78.6% nucleotide similarities with rabbit HEV isolates from Korea, the United States and France, respectively. To sum up, the HEV isolated in this study from farmed rabbits belongs to the HEV-3 genotype, and the zoonotic ability and pathogenesis of the rabbit HEV merit further study due to the fact that HEV-3 genotype has the potential to trigger zoonotic infections. es_ES
dc.description.sponsorship This study was supported by the Intramural Fund of Hebei University of Economics and Business in 2018 (2018PY17) and the Development Plan of Science and Technology of Tai’an, China (2016NS1051) es_ES
dc.language Inglés es_ES
dc.publisher Universitat Politècnica de València
dc.relation.ispartof World Rabbit Science
dc.rights Reserva de todos los derechos es_ES
dc.subject HEV es_ES
dc.subject Farmed rabbit es_ES
dc.subject RT-nPCR es_ES
dc.subject Phylogenetic analysis es_ES
dc.subject Nucleotide identity es_ES
dc.title Molecular features of hepatitis E virus from farmed rabbits in Shandong province, China es_ES
dc.type Artículo es_ES
dc.date.updated 2019-01-03T10:56:52Z
dc.identifier.doi 10.4995/wrs.2018.10225
dc.relation.projectID info:eu-repo/grantAgreement/Hebei University of Economics and Business//2018PY17/
dc.relation.projectID info:eu-repo/grantAgreement/Tai'an Science and Technology Development Plan//2016NS1051/ es_ES
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Zhang, H.; Zhou, Y.; Liu, J. (2018). Molecular features of hepatitis E virus from farmed rabbits in Shandong province, China. World Rabbit Science. 26(4):307-312. https://doi.org/10.4995/wrs.2018.10225 es_ES
dc.description.accrualMethod SWORD es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2018.10225 es_ES
dc.description.upvformatpinicio 307 es_ES
dc.description.upvformatpfin 312 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 26
dc.description.issue 4
dc.identifier.eissn 1989-8886
dc.contributor.funder Hebei University of Economics and Business
dc.contributor.funder Tai'an Science and Technology Development Plan es_ES
dc.contributor.funder International Science and Technology Cooperation Programme, China
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