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Engineered Functional Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes

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Engineered Functional Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes

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Ambros Palaguerri, S.; De La Iglesia Jordán, F.; Rosario, S.; Butkovic, A.; Elena Fito, SF. (2018). Engineered Functional Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes. Genome Biology and Evolution. 10(7):1823-1836. https://doi.org/10.1093/gbe/evy141

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/120638

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Title: Engineered Functional Redundancy Relaxes Selective Constraints upon Endogenous Genes in Viral RNA Genomes
Author:
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes
Issued date:
Abstract:
[EN] Functional redundancy, understood as the functional overlap of different genes, is a double-edge sword. At the one side, it is thought to serve as a robustness mechanism that buffers the deleterious effect of mutations ...[+]
Subjects: Compensatory evolution , Experimental virus evolution , Genetic redundancy , Multifunctional proteins , Tobacco etch virus , Viral suppressors of RNA silencing
Copyrigths: Reconocimiento - No comercial (by-nc)
Source:
Genome Biology and Evolution. (issn: 1759-6653 )
DOI: 10.1093/gbe/evy141
Publisher:
Oxford University Press
Publisher version: http://doi.org/10.1093/gbe/evy141
Thanks:
We thank Paula Agudo for excellent technical assistance. This work was supported by Spain's Agencia Estatal de Investigacion-FEDER grant BFU2015-65037-P to S.F.E. and by a fellowship from the Dominican Republic's Ministerio ...[+]
Type: Artículo

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