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Building blocks of a multi-layer PET with time sequence photon interaction discrimination and double Compton camera

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Building blocks of a multi-layer PET with time sequence photon interaction discrimination and double Compton camera

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dc.contributor.author Ilisie, V. es_ES
dc.contributor.author Giménez-Alventosa, Vicent es_ES
dc.contributor.author Moliner Martínez, Laura es_ES
dc.contributor.author Sánchez, F. es_ES
dc.contributor.author González Martínez, Antonio Javier es_ES
dc.contributor.author Rodríguez-Álvarez, M.J. es_ES
dc.contributor.author Benlloch Baviera, Jose María es_ES
dc.date.accessioned 2019-05-22T20:27:59Z
dc.date.available 2019-05-22T20:27:59Z
dc.date.issued 2018 es_ES
dc.identifier.issn 0168-9002 es_ES
dc.identifier.uri http://hdl.handle.net/10251/120917
dc.description.abstract [EN] Current PET detectors have a very low sensitivity, of the order of a few percent. One of the reasons is the fact that Compton interactions are rejected. If an event involves multiple Compton scattering and the total deposited energy lays within the photoelectric peak, then an energy-weighted centroid is the given output for the coordinates of the reconstructed interaction point. This introduces distortion in the final reconstructed image. The aim of our work is to prove that Compton events are a very rich source of additional information as one can improve the resolution of the detector and implicitly the final reconstructed image. This could be a real breakthrough for PET detector technology as one should be able to obtain better results with less patient radiation. Using a PET as a double Compton camera, by means of Compton cone matching i.e., Compton cones coming from the same event should be compatible, is applied to discard randoms, patient scattered events and also, to perform a correct matching among events with multiple coincidences. In order to fully benefit experimentally from Compton events using monolithic scintillators a multi-layer configuration is needed and a good time-of-flight resolution. es_ES
dc.description.sponsorship This project has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation programme (Grant Agreement No. 695536). This work was supported in part by the Spanish Government Grants TEC2016-79884-C2 and RTC-2016-5186-1. es_ES
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment es_ES
dc.rights Reconocimiento - No comercial - Sin obra derivada (by-nc-nd) es_ES
dc.subject PET es_ES
dc.subject Monolithic scintillator es_ES
dc.subject Compton camera es_ES
dc.subject TOF es_ES
dc.subject Multi-layer es_ES
dc.subject.classification LENGUAJES Y SISTEMAS INFORMATICOS es_ES
dc.subject.classification MATEMATICA APLICADA es_ES
dc.title Building blocks of a multi-layer PET with time sequence photon interaction discrimination and double Compton camera es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.nima.2018.03.076 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//TEC2016-79884-C2-1-R/ES/DESARROLLO DEL HARDWARE PARA SISTEMA DE DIAGNOSTICO POR IMAGEN MOLECULAR PARA CORAZON EN CONDICIONES DE ESTRES/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/695536/EU/Innovative PET scanner for dynamic imaging/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//RTC-2016-5186-1/ES/Control objetivo del deterioro cognitivo mediante análisis de imagen de amiloide/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Instrumentación para Imagen Molecular - Institut d'Instrumentació per a Imatge Molecular es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Matemática Aplicada - Departament de Matemàtica Aplicada es_ES
dc.description.bibliographicCitation Ilisie, V.; Giménez-Alventosa, V.; Moliner Martínez, L.; Sánchez, F.; González Martínez, AJ.; Rodríguez-Álvarez, M.; Benlloch Baviera, JM. (2018). Building blocks of a multi-layer PET with time sequence photon interaction discrimination and double Compton camera. Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment. 895:74-83. https://doi.org/10.1016/j.nima.2018.03.076 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion http://doi.org/10.1016/j.nima.2018.03.076 es_ES
dc.description.upvformatpinicio 74 es_ES
dc.description.upvformatpfin 83 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 895 es_ES
dc.relation.pasarela S\361436 es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES
dc.contributor.funder European Commission


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