- -

Quercetin directly promotes rabbit ovarian steroidogenesis

RiuNet: Repositorio Institucional de la Universidad Politécnica de Valencia

Compartir/Enviar a

Citas

Estadísticas

  • Estadisticas de Uso

Quercetin directly promotes rabbit ovarian steroidogenesis

Mostrar el registro sencillo del ítem

Ficheros en el ítem

dc.contributor.author Sirotkin, A.V. es_ES
dc.contributor.author Štochmaľová, A. es_ES
dc.contributor.author Grossmann, R. es_ES
dc.contributor.author Alwasel, S. es_ES
dc.contributor.author Harrath, A.H. es_ES
dc.date.accessioned 2019-10-02T08:18:15Z
dc.date.available 2019-10-02T08:18:15Z
dc.date.issued 2019-09-30
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/126963
dc.description.abstract [EN] The bioflavonoid quercetin is a component of food with numerous biological effects, but its function in reproductive processes remains to be investigated. This study aimed to examine the direct action of quercetin on steroid hormone release in rabbit ovaries. We analysed the effect of quercetin (0, 1, 10, and 100 ng/mL) on cultured rabbit ovarian fragments. The release of progesterone (P4), testosterone (T) and estradiol (E2) were analysed by enzyme immunoassay. Quercetin promoted P4, T, and E2 release by rabbit ovarian fragments. These observations indicate that quercetin can directly stimulate rabbit ovarian steroidogenesis – an essential regulator of reproduction and fecundity. The application of dietary quercetin for control of rabbit reproduction is discussed. es_ES
dc.language Inglés es_ES
dc.publisher Universitat Politècnica de València
dc.relation.ispartof World Rabbit Science
dc.rights Reserva de todos los derechos es_ES
dc.subject Nutrition es_ES
dc.subject Quercetin es_ES
dc.subject Ovary es_ES
dc.subject Steroids es_ES
dc.subject Rabbits es_ES
dc.title Quercetin directly promotes rabbit ovarian steroidogenesis es_ES
dc.type Artículo es_ES
dc.date.updated 2019-10-02T07:10:13Z
dc.identifier.doi 10.4995/wrs.2019.11816
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Sirotkin, A.; Štochmaľová, A.; Grossmann, R.; Alwasel, S.; Harrath, A. (2019). Quercetin directly promotes rabbit ovarian steroidogenesis. World Rabbit Science. 27(3):163-167. https://doi.org/10.4995/wrs.2019.11816 es_ES
dc.description.accrualMethod SWORD es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2019.11816 es_ES
dc.description.upvformatpinicio 163 es_ES
dc.description.upvformatpfin 167 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 27
dc.description.issue 3
dc.identifier.eissn 1989-8886
dc.description.references Anand D.A.V., Arulmoli R., Parasuraman S. 2016. Overviews of biological importance of quercetin: a bioactive flavonoid. Pharmacogn. Rev., 10: 84-89. https://doi.org/10.4103/0973-7847.194044 es_ES
dc.description.references Beazley K.E., Nurminskaya M. 2016. Effects of dietary quercetin on female fertility in mice: implication of transglutaminase 2. Reprod. Fertil. Dev., 28: 974-981. https://doi.org/10.1071/RD14155 es_ES
dc.description.references Boots A.W., Haenen G.R.M.M., Bast A. 2008. Health effect of quercetin: from antioxidant to nutraceutical. Eur. J. Pharmacol., 585: 325-337. https://doi.org/10.1016/j.ejphar.2008.03.008 es_ES
dc.description.references Chen C., Zhou, J.J., 2010a. Quercetin: A potential drug to reverse multidrug resistance. Life Sci., 87: 333-338. https://doi.org/10.1016/j.lfs.2010.07.004 es_ES
dc.description.references Chen Z.G., Luo L.L., Xu J.J., Zhuang X.L., Kong X.X., Fu Y.C., 2010b. Effects of plant polyphenols on ovarian follicular reserve in ageing rats. Biochem. Cell. Biol., 88: 737-45. https://doi.org/10.1139/O10-012 es_ES
dc.description.references Münster E. 1989. Entwicklung von enzymimmunologischen Messverfahren auf Mikrotitrationsplatten zur Bestimmung von Testosteron und Progesteron im Blutplasma. Doctoral Thesis. Institut for Animal Production and Breeding of the University of Hohemheim. 154. es_ES
dc.description.references Naseer Z., Ahmad E., Epikmen E.T., Uçan U., Boyacioğlu M., İpek E., Akosy M. 2017. Quercetin supplemented diet improves follicular development, oocyte quality, and reduces ovarian apoptosis in rabbits during summer heat stress. Theriogenology, 96: 136-141. https://doi.org/10.1016/j.theriogenology.2017.03.029 es_ES
dc.description.references Nna V.U., Usman U.Z., Ofutet E.O., Owu D.U. 2017. Quercetin exerts preventive, ameliorative and prophylactic effects on cadmium chloride - induced oxidative stress in the uterus and ovaries of female Wistar rats. Food Chem. Toxicol., 102: 143-155. https://doi.org/10.1016/j.fct.2017.02.010 es_ES
dc.description.references Prakash B.S., Meyer H.H., Schallenberger E., van de Wiel D.F. 1987. Development of a sensitive enzyme immunoassay (EIA) for progesterone determination in unextracted bovine plasma using the second antibody es_ES
dc.description.references technique. J. Steroid Biochem. Mol. Biol., 28: 623-627. https://doi.org/10.1016/0022-4731(87)90389-X es_ES
dc.description.references Rice S., Mason H.D., Whitehead S.A. 2006. Phytoestrogens and their low dose combinations inhibit mRNA expression and activity of aromatase in human granulosa-luteal cells. J. Steroid Biochem. Mol. Biol., 101: 216-225. https://doi.org/10.1016/j.jsbmb.2006.06.021 es_ES
dc.description.references Santini S.E., Basini G., Bussolati S., Grasselli F. 2009. The phytoestrogen quercetin impairs steroidogenesis and angiogenesis in swine granulosa cells in vitro. J. Biomed. Biotechnol., 2009: 419891. https://doi.org/10.1155/2009/419891 es_ES
dc.description.references Sharma A., Kashyap D., Sak K., Tuli H.S., Sharma A.K. 2018. Therapeutic charm of quercetin and its derivatives: a review of research and patents. Pharm. Pat. Anal., 7: 15-32. https://doi.org/10.4155/ppa-2017-0030 es_ES
dc.description.references Shu X., Hu X.J., Zhou S.Y., Xu C.L., Qiu Q.Q., Nie S.P., Xie M.Y. 2011. [Effect of quercetin exposure during the prepubertal period on ovarian development and reproductive endocrinology of mice]. Yao Xue Xue Bao, 46: 1051-1057. es_ES
dc.description.references Sirotkin A.V. 2014. Regulators of ovarian functions. New York: Nova Science Publishers Inc. 194, ISBN 978-1-62948-574-4. es_ES
dc.description.references Sirotkin A.V., Harrath A.H. 2014. Phytoestrogens and their effects. Eur J Pharmacol., 741: 230-236. https://doi.org/10.1016/j. ejphar.2014.07.057 es_ES
dc.description.references Sirotkin A.V., Chrenek P., Kolesarová A., Parillo F., Zerani M., Boiti C. 2014. Novel regulators of rabbit reproductive functions. Anim. Reprod. Sci., 148: 188-196. https://doi.org/10.1016/j.anireprosci.2014.06.001 es_ES
dc.description.references Sirotkin A.V., Kadasi A., Stochmalova A., Balazi A., Földesiová M., Makovicky P., Chrenek P., Harrath A.H. 2017. Effect of turmeric on the viability, ovarian folliculogenesis, fecundity, ovarian hormones and response to luteinizing hormone of rabbits. Animal. 26: 1-8. https://doi.org/10.1017/S175173111700235X es_ES
dc.description.references van Duursen M.B.M. 2017. Modulation of estrogen synthesis and metabolism by phytoestrogens in vitro and the implications for women's health. Toxicol Res (Camb)., 6: 772-794. https://doi.org/10.1039/C7TX00184C es_ES
dc.description.references Walgren R.A., Lin J.T., Kinne R.K., Walle T. 2000. Cellular uptake of dietary flavonoid quercetin 4'-beta-glucoside by sodiumdependent glucose transporter SGLT1. J. Pharmacol. Exp. Ther., 294: 837-843. es_ES
dc.description.references Whitehead S.A., Lacey M. 2003. Phytoestrogens inhibit aromatase but not 17beta-hydroxysteroid dehydrogenase (HSD) type 1 in human granulosa-luteal cells: evidence for FSH induction of 17beta-HSD. Hum. Reprod.,18: 487-494. https://doi.org/10.1093/humrep/deg125 es_ES


Este ítem aparece en la(s) siguiente(s) colección(ones)

Mostrar el registro sencillo del ítem