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Identification of two novel single nucleotide polymorphism sites in the Myostatin (MSTN) gene and their association with carcass traits in meat-type rabbits (Oryctolagus cuniculus)

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Identification of two novel single nucleotide polymorphism sites in the Myostatin (MSTN) gene and their association with carcass traits in meat-type rabbits (Oryctolagus cuniculus)

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dc.contributor.author Yang, L.Q es_ES
dc.contributor.author Zhang, K. es_ES
dc.contributor.author Wu, Q. Y es_ES
dc.contributor.author Li, J. es_ES
dc.contributor.author Lai, S. J es_ES
dc.contributor.author Song, T. Z es_ES
dc.contributor.author Zhang, M. es_ES
dc.date.accessioned 2020-02-27T11:37:15Z
dc.date.available 2020-02-27T11:37:15Z
dc.date.issued 2019-12-23
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/137912
dc.description.abstract [EN] Two unknown single nucleotide polymorphism (SNP) sites in exons 1 (c.194C>T) and 2 (c.445T>A) of meat-type rabbit MSTN gene were identified in the study. Our objective was to analyse the population genetics structure of the two novel SNP sites in 230 individuals from six breeds and their associations with carcass traits of rabbits. We found that live body weight (BW), cold carcass weight (CCW), reference carcass weight (RCW), CCW percentage (PCCW) and RCW percentage (PRCW) of the rabbits with the genotype CC at the c.194C>T of exon 1 or AA at the c.445T>A of exon 2 were significantly higher than those with other genotypes. Diplotype significantly affected BW, RCW, CCW, PRCW (P<0.01) and PCCW and PCM (P<0.05). CC/AA was the advantageous diplotype for BW, RCW, CCW and PCM, and TT/AA was the advantageous diplotype for PCCW and PRCW. In contrast, TT/TT was the negative diplotype for BW, CCW, RCW, PCCW and PRCW, and TT/AA was the negative diplotype for PCM. The results sug es_ES
dc.description.sponsorship The studies were financially supported by Basic Science Research Fund of Sichuan Agricultural University (No.11967) and the National Modern Rabbit Production Industry Special Fund (N°. NYCYTX-44-1-3). es_ES
dc.language Inglés es_ES
dc.publisher Universitat Politècnica de València es_ES
dc.relation.ispartof World Rabbit Science es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Rabbit es_ES
dc.subject Myostatin gene es_ES
dc.subject Single nucleotide polymorphisms es_ES
dc.subject Carcass traits es_ES
dc.title Identification of two novel single nucleotide polymorphism sites in the Myostatin (MSTN) gene and their association with carcass traits in meat-type rabbits (Oryctolagus cuniculus) es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.4995/wrs.2019.10610
dc.relation.projectID info:eu-repo/grantAgreement/SICAU//11967/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/National Modern Rabbit Production Industry Special Fund//NYCYTX-44-1-3/ es_ES
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Yang, L.; Zhang, K.; Wu, QY.; Li, J.; Lai, SJ.; Song, TZ.; Zhang, M. (2019). Identification of two novel single nucleotide polymorphism sites in the Myostatin (MSTN) gene and their association with carcass traits in meat-type rabbits (Oryctolagus cuniculus). World Rabbit Science. 27(4):249-256. https://doi.org/10.4995/wrs.2019.10610 es_ES
dc.description.accrualMethod OJS es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2019.10610 es_ES
dc.description.upvformatpinicio 249 es_ES
dc.description.upvformatpfin 256 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 27 es_ES
dc.description.issue 4 es_ES
dc.identifier.eissn 1989-8886
dc.relation.pasarela OJS\10610 es_ES
dc.contributor.funder Sichuan Agricultural University es_ES
dc.contributor.funder National Modern Rabbit Production Industry Special Fund es_ES
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