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Early postmortem gene expression and its relationship to composition and quality traits in pig Longissimus dorsi muscle

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Early postmortem gene expression and its relationship to composition and quality traits in pig Longissimus dorsi muscle

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dc.contributor.author Cánovas, A. es_ES
dc.contributor.author Varona, L. es_ES
dc.contributor.author Burgos, C. es_ES
dc.contributor.author Galve, A. es_ES
dc.contributor.author Carrodeguas, J. A. es_ES
dc.contributor.author Ibáñez-Escriche, Noelia es_ES
dc.contributor.author Martin-Burriel, I. es_ES
dc.contributor.author López-Buesa, P. es_ES
dc.date.accessioned 2020-03-12T06:51:43Z
dc.date.available 2020-03-12T06:51:43Z
dc.date.issued 2012-10 es_ES
dc.identifier.issn 0021-8812 es_ES
dc.identifier.uri http://hdl.handle.net/10251/138739
dc.description.abstract [EN] An mRNA expression study has been performed in 20-to 25-min postmortem-obtained samples from Longissimus dorsi muscle of 59 Duroc x Landrace/Large White (LD/LW) pigs to search for gene sequences related to meat quality (pH(24), pH(45), "Lab" color coordinates, curing yield, and exudation at 3 different times) or meat composition [intramuscular fat, content of several fatty acids (C16:0, C18:0, C18:1, and C18:2), ratio of saturated, monounsaturated, and polyunsaturated fatty acids, and protein and humidity contents] traits to find targets for selection. Gene ontology analysis, biological pathway, and gene network studies all show that many more differentially expressed genes (506 vs. 279) are related to meat quality (Group P or perimortem characters) than to meat composition traits (Group L or whole life traits). The difference between the number of gene ontology terms annotated, biological pathways, and gene networks in groups P and L is notable due to the differences in the complexity of the "generation process" of P-traits and involvement of other tissues or organs in the generation of variability of L-traits. Also, interactions between differentially expressed genes were found in extracellular matrix (ECM)-receptor interaction, tumor growth factor (TGF)-beta signaling pathway, fatty acid elongation in mitochondria, and adipocytokine signaling pathway, indicating that a substantial fraction of the gene networks could be associated with interactions between differentially expressed genes related to traits under study. A large number of the most overexpressed genes are related to muscle development and functionality and repair mechanisms; they could be good candidates for breeding programs in which the main goal is to enhance meat quality. es_ES
dc.description.sponsorship This work was supported by projects Diputacion General de Aragon PI043/09 to Luis Varona Aguado and AGL2008-01487 ALI to Pascual Lopez Buesa. Almudena Galve thanks the Diputacion General de Aragon for a predoctoral fellowship. es_ES
dc.language Inglés es_ES
dc.publisher American Society of Animal Science es_ES
dc.relation.ispartof Journal of Animal Science es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Composition es_ES
dc.subject Genetic selection es_ES
dc.subject MRNA microarray es_ES
dc.subject Pork es_ES
dc.subject Quality es_ES
dc.subject.classification PRODUCCION ANIMAL es_ES
dc.title Early postmortem gene expression and its relationship to composition and quality traits in pig Longissimus dorsi muscle es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.2527/jas.2011-4799 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/Gobierno de Aragón//PI043%2F09/ES/Determinación mediante análisis de expresión génica de un panel de genes candidatos para los procesos de miogénesis e infiltración grasa en cerdos de la denominación de origen Jamón de Teruel./ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MICINN//AGL2008-01487/ES/INFLUENCIA DE IGF2, MC4R Y PEPCK SOBRE LA INFILTRACION GRASA DE LA CANAL Y DE LA CARNE DE CERDO/ es_ES
dc.rights.accessRights Cerrado es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ciencia Animal - Departament de Ciència Animal es_ES
dc.description.bibliographicCitation Cánovas, A.; Varona, L.; Burgos, C.; Galve, A.; Carrodeguas, JA.; Ibáñez-Escriche, N.; Martin-Burriel, I.... (2012). Early postmortem gene expression and its relationship to composition and quality traits in pig Longissimus dorsi muscle. Journal of Animal Science. 90(10):3325-3336. https://doi.org/10.2527/jas.2011-4799 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.2527/jas.2011-4799 es_ES
dc.description.upvformatpinicio 3325 es_ES
dc.description.upvformatpfin 3336 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 90 es_ES
dc.description.issue 10 es_ES
dc.relation.pasarela S\395259 es_ES
dc.contributor.funder Diputación General de Aragón es_ES
dc.contributor.funder Ministerio de Ciencia e Innovación es_ES
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