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Novel method to measure the intrinsic spatial resolution in PET detectors based on monolithic crystals

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Novel method to measure the intrinsic spatial resolution in PET detectors based on monolithic crystals

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dc.contributor.author González, A. es_ES
dc.contributor.author Sanchez, Filomeno es_ES
dc.contributor.author Bruyndonckx, Peter es_ES
dc.contributor.author Cañizares-Ledo, Gabriel es_ES
dc.contributor.author Benlloch Baviera, Jose María es_ES
dc.contributor.author González Martínez, Antonio Javier es_ES
dc.date.accessioned 2020-04-17T12:48:27Z
dc.date.available 2020-04-17T12:48:27Z
dc.date.issued 2019-03-11 es_ES
dc.identifier.issn 0168-9002 es_ES
dc.identifier.uri http://hdl.handle.net/10251/140848
dc.description.abstract [EN] The main aim of this work is to provide a method to retrieve the intrinsic spatial resolution of a gamma-ray detector block based on monolithic crystals within an assembled scanner. This method consists on a discrimination of the data using a software collimation process. The results are compared with an alternative method of separating two detector blocks far enough to produce a "virtual" source collimation due to the geometric constraints on the allowed coincidence event angles. A theoretical model has been deduced to fit the measured light distribution profiles, allowing estimating the detector intrinsic spatial resolution. The detector intrinsic spatial resolution is expected to follow a Gaussian distribution and the positron-emitter source shape, given the small size of a Na-22 source with 0.25 mm in diameter, can be assumed to follow a Lorentzian profile. However, the collimation of the data modifies the source shape that is no longer a pure Lorentzian distribution. Therefore, the model is based on the convolution of a Gaussian shaped distribution (contribution of the detector) and a modified Lorentzian distribution (contribution of the collimated source profile) that takes into account the collimation effect. Three LYSO crystals geometries have been studied in the present work, namely a 10 mm thick trapezoidal monolithic block, and two rectangular monolithic blocks with thicknesses of 15 mm and 20 mm, respectively. All the blocks have size dimensions of 50 mm x 50 mm. The experimental results yielded an intrinsic detector spatial resolution of 0.64 +/- 0.02 mm, 0.82 +/- 0.02 and 1.07 +/- 0.03 mm, for the 10 mm, 15 mm and 20 mm thick blocks, respectively, when the source was placed at the center of the detector. The detector intrinsic spatial resolution was moreover evaluated across one of the axis of each crystal. These values worsen to an average value of 0.68 +/- 0.04 mm, 0.90 +/- 0.14 and 1.29 +/- 0.19 mm, respectively, when the whole crystal size is considered, as expected. These tests show an accurate method to determine the intrinsic spatial resolution of monolithic-based detector blocks, once assembled in the PET system. es_ES
dc.description.sponsorship This project has received funding from the European Research Council, Spain (ERC) under the European Union's Horizon 2020 research and innovation program (grant agreement No 695536). It has also been supported by the EU, Spain Grant 603002 under the FP7 program, and by the Spanish Ministerio de Economia, Industria y Competitividad under Grant TEC2016-79884-C2-1-R and through PROSPET (DTS15/00152) funded by the Ministerio de Economia y Competitividad, Spain. es_ES
dc.language Inglés es_ES
dc.publisher Elsevier es_ES
dc.relation.ispartof Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Gamma ray detectors es_ES
dc.subject Positron Emission Tomography es_ES
dc.subject Intrinsic spatial resolution es_ES
dc.subject SiPM array es_ES
dc.subject Monolithic blocks es_ES
dc.title Novel method to measure the intrinsic spatial resolution in PET detectors based on monolithic crystals es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1016/j.nima.2018.12.056 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//DTS15%2F00152/ES/Desarrollo de un detector PET para guiar la biopsia, el tratamiento y el seguimiento del cáncer de próstata (PROSPECT)/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/FP7/603002/EU/Multimodal Imaging of Neurological Disorders/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//TEC2016-79884-C2-1-R/ES/DESARROLLO DEL HARDWARE PARA SISTEMA DE DIAGNOSTICO POR IMAGEN MOLECULAR PARA CORAZON EN CONDICIONES DE ESTRES/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/695536/EU/Innovative PET scanner for dynamic imaging/
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto de Instrumentación para Imagen Molecular - Institut d'Instrumentació per a Imatge Molecular es_ES
dc.contributor.affiliation Universitat Politècnica de València. Instituto Universitario Mixto de Biología Molecular y Celular de Plantas - Institut Universitari Mixt de Biologia Molecular i Cel·lular de Plantes es_ES
dc.description.bibliographicCitation González, A.; Sanchez, F.; Bruyndonckx, P.; Cañizares-Ledo, G.; Benlloch Baviera, JM.; González Martínez, AJ. (2019). Novel method to measure the intrinsic spatial resolution in PET detectors based on monolithic crystals. Nuclear Instruments and Methods in Physics Research Section A Accelerators Spectrometers Detectors and Associated Equipment. 920:58-67. https://doi.org/10.1016/j.nima.2018.12.056 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1016/j.nima.2018.12.056 es_ES
dc.description.upvformatpinicio 58 es_ES
dc.description.upvformatpfin 67 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 920 es_ES
dc.relation.pasarela S\406016 es_ES
dc.contributor.funder European Commission es_ES
dc.contributor.funder Ministerio de Economía y Competitividad


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