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A Tangible Educative 3D Printed Atlas of the Rat Brain

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A Tangible Educative 3D Printed Atlas of the Rat Brain

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dc.contributor.author Quiñones, Darío R. es_ES
dc.contributor.author Ferragud-Agulló, Jorge es_ES
dc.contributor.author Pérez Feito, Ricardo es_ES
dc.contributor.author García Manrique, Juan Antonio es_ES
dc.contributor.author Canals-Gamoneda, Santiago es_ES
dc.contributor.author Moratal, David es_ES
dc.date.accessioned 2020-05-06T07:17:45Z
dc.date.available 2020-05-06T07:17:45Z
dc.date.issued 2018-09 es_ES
dc.identifier.uri http://hdl.handle.net/10251/142512
dc.description.abstract [EN] In biology and neuroscience courses, brain anatomy is usually explained using Magnetic Resonance (MR) images or histological sections of different orientations. These can show the most important macroscopic areas in an animals¿ brain. However, this method is neither dynamic nor intuitive. In this work, an anatomical 3D printed rat brain with educative purposes is presented. Hand manipulation of the structure, facilitated by the scale up of its dimensions, and the ability to dismantle the ¿brain¿ into some of its constituent parts, facilitates the understanding of the 3D organization of the nervous system. This is an alternative method for teaching students in general and biologists in particular the rat brain anatomy. The 3D printed rat brain has been developed with eight parts, which correspond to the most important divisions of the brain. Each part has been fitted with interconnections, facilitating assembling and disassembling as required. These solid parts were smoothed out, modified and manufactured through 3D printing techniques with poly(lactic acid) (PLA). This work presents a methodology that could be expanded to almost any field of clinical and pre-clinical research, and moreover it avoids the need for dissecting animals to teach brain anatomy. es_ES
dc.description.sponsorship This work was supported in part by the Spanish Ministerio de Economia y Competitividad (MINECO) and FEDER funds under grants BFU2015-64380-C2-2-R (D.M.) and BFU2015-64380-C2-1-R and EU Horizon 2020 Program 668863-SyBil-AA grant (S.C.). S.C. acknowledges financial support from the Spanish State Research Agency, through the "Severo Ochoa" Programme for Centres of Excellence in R&D (ref. SEV-2013-0317). D.R.Q. was supported by grant "Ayudas para la formacion de personal investigador (FPI)" from the Vicerrectorado de Investigacion, Innovacion y Transferencia of the Universitat Politecnica de Valencia. es_ES
dc.language Inglés es_ES
dc.publisher MDPI AG es_ES
dc.relation.ispartof Materials es_ES
dc.rights Reconocimiento (by) es_ES
dc.subject Brain es_ES
dc.subject Rapid prototyping es_ES
dc.subject Atlas es_ES
dc.subject Rat es_ES
dc.subject Magnetic resonance imaging es_ES
dc.subject Educative model es_ES
dc.subject.classification INGENIERIA DE LOS PROCESOS DE FABRICACION es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title A Tangible Educative 3D Printed Atlas of the Rat Brain es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.3390/ma11091531 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/EC/H2020/668863/EU/Systems Biology of Alcohol Addiction: Modeling and validating disease state networks in human and animal brains for understanding pathophysiolgy, predicting outcomes and improving therapy/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//BFU2015-64380-C2-1-R/ES/TRATAR LA ENFERMEDAD RESINTONIZANDO LA DINAMICA DE LAS REDES CEREBRALES/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//SEV-2013-0317/ES/-/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Mecánica y de Materiales - Departament d'Enginyeria Mecànica i de Materials es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.description.bibliographicCitation Quiñones, DR.; Ferragud-Agulló, J.; Pérez Feito, R.; García Manrique, JA.; Canals-Gamoneda, S.; Moratal, D. (2018). A Tangible Educative 3D Printed Atlas of the Rat Brain. Materials. 11(9):1531-1542. https://doi.org/10.3390/ma11091531 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.3390/ma11091531 es_ES
dc.description.upvformatpinicio 1531 es_ES
dc.description.upvformatpfin 1542 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 11 es_ES
dc.description.issue 9 es_ES
dc.identifier.eissn 1996-1944 es_ES
dc.identifier.pmid 30149609 es_ES
dc.relation.pasarela S\367453 es_ES
dc.contributor.funder European Regional Development Fund es_ES
dc.contributor.funder Universitat Politècnica de València es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES
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