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Impact of quercetin supplementation on testicular functions in summer heat-stressed rabbits

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Impact of quercetin supplementation on testicular functions in summer heat-stressed rabbits

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dc.contributor.author Naseer, Z. es_ES
dc.contributor.author Ahmad, E. es_ES
dc.contributor.author Aksoy, M. es_ES
dc.contributor.author Epikmen, E.T. es_ES
dc.coverage.spatial east=174.885971; north=-40.90055699999999; name=Nova Zelanda es_ES
dc.date.accessioned 2020-05-13T11:16:04Z
dc.date.available 2020-05-13T11:16:04Z
dc.date.issued 2020-03-31
dc.identifier.issn 1257-5011
dc.identifier.uri http://hdl.handle.net/10251/143072
dc.description.abstract [EN] The current study was designed to determine the effects of dietary quercetin on epididymal sperm and testicular changes in male rabbits during summer heat stress (HS). Twelve adult male New Zealand white rabbits were submitted to summer heat conditions (temperature-humidity index 29.9±1.2). One group was fed a basal ration (BR; n=6), whereas the other group was fed the same basal diet supplemented with quercetin (30 mg/kg d; Que-BR; n=6) for 60 d, and both groups were sacrificed at the end of the experiment. Epididymis and testicles isolation was done for sperm, histopathology and apoptosis assessments. The results showed that quercetin improved epididymis weight, but did not affect other testicular dimensions except testicular length. A significant improvement was observed in epididymal sperm motility, concentration, kinematic parameters, viability, mitochondrial potential and acrosome integrity in Que-BR compared to the BR group. Lowered serum malondialdehyde level was observed in quercetin supplemented rabbits. Moreover, the quercetin supplementation maintained the interstitial stroma, seminiferous tubules architecture, germinal and Sertoli cells under HS, decreasing the apoptotic germ cell rate in seminiferous tubules. In conclusion, HS condition affects the sperm and testes configurations in rabbits and dietary quercetin minimises oxidative stress, which in turn protects the testes and sperm against HS induced damage. es_ES
dc.description.sponsorship The financial support for this work was granted by ADU-BAP, Project number VTF-15034, Adnan Menderes University, Aydin, Turkey. es_ES
dc.language Inglés es_ES
dc.publisher Universitat Politècnica de València es_ES
dc.relation.ispartof World Rabbit Science es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject Quercetin es_ES
dc.subject Heat stress es_ES
dc.subject Testes es_ES
dc.subject Sperm es_ES
dc.subject Apoptosis es_ES
dc.subject Rabbit es_ES
dc.title Impact of quercetin supplementation on testicular functions in summer heat-stressed rabbits es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.4995/wrs.2020.12420
dc.relation.projectID info:eu-repo/grantAgreement/Adnan Menderes University//ADU-BAP-VTF-15034/ / es_ES
dc.rights.accessRights Abierto es_ES
dc.description.bibliographicCitation Naseer, Z.; Ahmad, E.; Aksoy, M.; Epikmen, E. (2020). Impact of quercetin supplementation on testicular functions in summer heat-stressed rabbits. World Rabbit Science. 28(1):19-27. https://doi.org/10.4995/wrs.2020.12420 es_ES
dc.description.accrualMethod OJS es_ES
dc.relation.publisherversion https://doi.org/10.4995/wrs.2020.12420 es_ES
dc.description.upvformatpinicio 19 es_ES
dc.description.upvformatpfin 27 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 28 es_ES
dc.description.issue 1 es_ES
dc.identifier.eissn 1989-8886
dc.relation.pasarela OJS\12420 es_ES
dc.contributor.funder Adnan Menderes University es_ES
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