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Design of oligonucleotide-capped mesoporous silica nanoparticles for the detection of miRNA-145 by duplex and triplex formation

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Design of oligonucleotide-capped mesoporous silica nanoparticles for the detection of miRNA-145 by duplex and triplex formation

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Ribes, À.; Santiago Felipe, S.; Aviñó, A.; Candela-Noguera, V.; Eritja, R.; Sancenón Galarza, F.; Martínez-Máñez, R.... (2018). Design of oligonucleotide-capped mesoporous silica nanoparticles for the detection of miRNA-145 by duplex and triplex formation. Sensors and Actuators B Chemical. 277:598-603. https://doi.org/10.1016/j.snb.2018.09.026

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Title: Design of oligonucleotide-capped mesoporous silica nanoparticles for the detection of miRNA-145 by duplex and triplex formation
Author:
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Universitat Politècnica de València. Departamento de Ingeniería Mecánica y de Materiales - Departament d'Enginyeria Mecànica i de Materials
Issued date:
Embargo end date: 2020-12-20
Abstract:
[EN] The development of new strategies to detect microRNAs (miRNAS) has become an important challenge in thebiomedical ¿eld. We report herein the use of oligonucleotide-gated silica nanoparticles for the detection ofmiRNA-145. ...[+]
Subjects: Mesoporous silica materials , Molecular gates , MiRNA-145 , Biosensor , Triplex
Copyrigths: Embargado
Source:
Sensors and Actuators B Chemical. (issn: 0925-4005 )
DOI: 10.1016/j.snb.2018.09.026
Publisher:
Elsevier
Publisher version: https://doi.org/10.1016/j.snb.2018.09.026
Thanks:
We thank the Spanish Government (projects MAT2015-64139-C4-1-R and CTQ2014-52588-R (MINECO/FEDER)), the Generalitat Valenciana (project PROMETEOII/2014/047) and the Generalitat de Catalunya (2014/SGR/624) for support. A.R. ...[+]
Type: Artículo

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