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Enhanced Drug Photosafety by Interchromophoric Interaction Due to Intramolecular Charge Separation

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Enhanced Drug Photosafety by Interchromophoric Interaction Due to Intramolecular Charge Separation

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Li, M.; Yan, Z.; Zhu, R.; Phillips, DL.; Aparici-Espert, MI.; Lhiaubet, VL.; Miranda Alonso, MÁ. (2018). Enhanced Drug Photosafety by Interchromophoric Interaction Due to Intramolecular Charge Separation. Chemistry - A European Journal. 24(25):6654-6659. https://doi.org/10.1002/chem.201800716

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/143880

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Title: Enhanced Drug Photosafety by Interchromophoric Interaction Due to Intramolecular Charge Separation
Author: Li, Ming-De Yan, Zhiping Zhu, Ruixue Phillips,David Lee Aparici-Espert, Maria Isabel Lhiaubet, Virginie Lyria Miranda Alonso, Miguel Ángel
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
[EN] Imatinib is a synthetic tyrosinase inhibitor that is employed for the treatment of some kinds of human cancer. This drug has a low phototoxicity towards DNA, but its pyridylpyrimidine (1) fragment by itself exhibits ...[+]
Subjects: Absorption , Charge separation , Chromophores , Electronic structure , Raman spectroscopy
Copyrigths: Reserva de todos los derechos
Source:
Chemistry - A European Journal. (issn: 0947-6539 )
DOI: 10.1002/chem.201800716
Publisher:
John Wiley & Sons
Publisher version: https://doi.org/10.1002/chem.201800716
Thanks:
This work was supported by Natural Science Foundation of China (21773151) and Shantou University Initial Funding (NTF16010). The Support from the Hong Kong Research Grants Council grants GRF 17307916, AoE/P-03/08, SEG ...[+]
Type: Artículo

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