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Differential Modulation of I-K and I-Ca,I-L Channels in High-Fat Diet-Induced Obese Guinea Pig Atria

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Differential Modulation of I-K and I-Ca,I-L Channels in High-Fat Diet-Induced Obese Guinea Pig Atria

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Martínez-Mateu, L.; Saiz Rodríguez, FJ.; Aromolaran, A. (2019). Differential Modulation of I-K and I-Ca,I-L Channels in High-Fat Diet-Induced Obese Guinea Pig Atria. Frontiers in Physiology. 10:1-18. https://doi.org/10.3389/fphys.2019.01212

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/145544

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Title: Differential Modulation of I-K and I-Ca,I-L Channels in High-Fat Diet-Induced Obese Guinea Pig Atria
Author: Martínez-Mateu, Laura Saiz Rodríguez, Francisco Javier Aromolaran, Ademuyiwa S.
UPV Unit: Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica
Issued date:
Abstract:
[EN] Obesity mechanisms that make atrial tissue vulnerable to arrhythmia are poorly understood. Voltage-dependent potassium (I-K, I-Kur, and I-K1) and L-type calcium currents (I-Ca,I- L) are electrically relevant and ...[+]
Subjects: High-fat diet , HERG , KCNQ1 , Cardiomyocytes , Guinea pig , Atria
Copyrigths: Reconocimiento (by)
Source:
Frontiers in Physiology. (issn: 1664-042X )
DOI: 10.3389/fphys.2019.01212
Publisher:
Frontiers Media SA
Publisher version: https://doi.org/10.3389/fphys.2019.01212
Project ID:
info:eu-repo/grantAgreement/AHA//13SDG16850065/
info:eu-repo/grantAgreement/NIH//R01HL147044/
info:eu-repo/grantAgreement/GVA//PROMETEO%2F2016%2F088/ES/MODELOS COMPUTACIONALES PERSONALIZADOS MULTI-ESCALA PARA LA OPTIMIZACION DEL DIAGNOSTICO Y TRATAMIENTO DE ARRITMIAS CARDIACAS (PERSONALISED DIGITAL HEART)/
Thanks:
This study was supported by an AHA (13SDG16850065 to AA), NIH (R01 HL147044 to AA), and Programa Prometeu de la Conselleria d Educació, Formació I Ocupació de la Generalitat Valenciana, award number PROMETEU/2016/088.
Type: Artículo

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