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Indirect calculation of monoclonal antibodies in nanoparticles using the radiolabeling process with technetium 99 metastable as primary factor: Alternative methodology for the entrapment efficiency

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Indirect calculation of monoclonal antibodies in nanoparticles using the radiolabeling process with technetium 99 metastable as primary factor: Alternative methodology for the entrapment efficiency

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Helal-Neto, E.; Sánchez-Cabezas, S.; Sancenón Galarza, F.; Martínez-Máñez, R.; Santos-Oliveira, R. (2018). Indirect calculation of monoclonal antibodies in nanoparticles using the radiolabeling process with technetium 99 metastable as primary factor: Alternative methodology for the entrapment efficiency. Journal of Pharmaceutical and Biomedical Analysis. 153:90-94. https://doi.org/10.1016/j.jpba.2018.02.017

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/146166

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Title: Indirect calculation of monoclonal antibodies in nanoparticles using the radiolabeling process with technetium 99 metastable as primary factor: Alternative methodology for the entrapment efficiency
Author: Helal-Neto, E. Sánchez-Cabezas, Santiago Sancenón Galarza, Félix Martínez-Máñez, Ramón Santos-Oliveira, Ralph
UPV Unit: Universitat Politècnica de València. Departamento de Química - Departament de Química
Issued date:
Abstract:
[EN] The use of monoclonal antibodies (Mab) in the current medicine is increasing. Antibody-drug conjugates (ADCs) represents an increasingly and important modality for treating several types of cancer. In this area, the ...[+]
Subjects: Nanoparticles , Magnetic core mesoporous silica , Nanoparticles doped with trastuzumab and labeled with Tc-99m , Cancer , Oncology , Smart device
Copyrigths: Reserva de todos los derechos
Source:
Journal of Pharmaceutical and Biomedical Analysis. (issn: 0731-7085 )
DOI: 10.1016/j.jpba.2018.02.017
Publisher:
Elsevier
Publisher version: https://doi.org/10.1016/j.jpba.2018.02.017
Thanks:
The authors would like to thank the National Scientific and Technological Research Council (CNPQ) and the Rio de Janeiro State Research Foundation (FAPERJ) for funding. Authors also gratefully acknowledge the financial ...[+]
Type: Artículo

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