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Safe approaches for camptothecin delivery: Structural analogues and nanomedicines

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Safe approaches for camptothecin delivery: Structural analogues and nanomedicines

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Botella Asuncion, P.; Rivero-Buceta, EM. (2017). Safe approaches for camptothecin delivery: Structural analogues and nanomedicines. Journal of Controlled Release. 247:28-54. https://doi.org/10.1016/j.jconrel.2016.12.023

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/148360

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Title: Safe approaches for camptothecin delivery: Structural analogues and nanomedicines
Author: BOTELLA ASUNCION, PABLO Rivero-Buceta, Eva María
UPV Unit: Universitat Politècnica de València. Instituto Universitario Mixto de Tecnología Química - Institut Universitari Mixt de Tecnologia Química
Issued date:
Abstract:
[EN] Twenty-(S)-camptothecin is a strongly cytotoxic molecule with excellent antitumor activity over a wide spectrum of human cancers. However, the direct formulation is limited by its poor water solubility, low plasmatic ...[+]
Subjects: Camptothecin analogues , Camptothecin nanomedicines , Structure-activity relationship , Stimuli-responsive , Clinical trials
Copyrigths: Reconocimiento - No comercial - Sin obra derivada (by-nc-nd)
Source:
Journal of Controlled Release. (issn: 0168-3659 )
DOI: 10.1016/j.jconrel.2016.12.023
Publisher:
Elsevier
Publisher version: https://doi.org/10.1016/j.jconrel.2016.12.023
Project ID:
MINECO/MAT2012-39290-C02-02
MINECO/SEV 2012-0267
Thanks:
Financial support of the Spanish Ministry of Economy and Competitiveness (projects MAT2012-39290-C02-02 and SEV-2012-0267) is gratefully acknowledged. Dr. E.M. Rivero thanks the Cursol Foundation for a post-doctoral scholarship.[+]
Type: Artículo

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