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Broadening the antibacterial spectrum of histidine kinase autophosphorylation inhibitors via the use of epsilon-poly-L-lysine capped mesoporous silica-based nanoparticles

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Broadening the antibacterial spectrum of histidine kinase autophosphorylation inhibitors via the use of epsilon-poly-L-lysine capped mesoporous silica-based nanoparticles

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Velikova, N.; Mas Font, N.; Miguel-Romero, L.; Polo, L.; Stolte, E.; Zaccaria, E.; Cao, R.... (2017). Broadening the antibacterial spectrum of histidine kinase autophosphorylation inhibitors via the use of epsilon-poly-L-lysine capped mesoporous silica-based nanoparticles. Nanomedicine Nanotechnology Biology and Medicine. 13(2):569-581. https://doi.org/10.1016/j.nano.2016.09.011

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/148516

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Title: Broadening the antibacterial spectrum of histidine kinase autophosphorylation inhibitors via the use of epsilon-poly-L-lysine capped mesoporous silica-based nanoparticles
Author: Velikova, Nadya Mas Font, Nuria MIguel-Romero, Laura Polo, Lorena Stolte, Ellen Zaccaria, Edoardo Cao, Rui Taverne, Nico Murguía, Jose R. Martínez-Máñez, Ramón Marina, Alberto Wells, Jerry
UPV Unit: Universitat Politècnica de València. Departamento de Biotecnología - Departament de Biotecnologia
Universitat Politècnica de València. Departamento de Química - Departament de Química
Universitat Politècnica de València. Departamento de Proyectos de Ingeniería - Departament de Projectes d'Enginyeria
Issued date:
Abstract:
[EN] Two-component systems (TCS) regulate diverse processes such as virulence, stress responses, metabolism and antibiotic resistance in bacteria but are absent in humans, making them promising targets for novel antibacterials. ...[+]
Subjects: Multi-drug resistance , Gram negative , Nanotechnology , Drug delivery , Two-component systems
Copyrigths: Reconocimiento - No comercial - Sin obra derivada (by-nc-nd)
Source:
Nanomedicine Nanotechnology Biology and Medicine. (issn: 1549-9634 )
DOI: 10.1016/j.nano.2016.09.011
Publisher:
Elsevier
Publisher version: https://doi.org/10.1016/j.nano.2016.09.011
Project ID:
info:eu-repo/grantAgreement/EC/FP7/238490/EU/Scientific Training in Antimicrobial Research Strategies/
...[+]
info:eu-repo/grantAgreement/EC/FP7/238490/EU/Scientific Training in Antimicrobial Research Strategies/
info:eu-repo/grantAgreement/MINECO//MAT2015-64139-C4-1-R/ES/NANOMATERIALES INTELIGENTES, SONDAS Y DISPOSITIVOS PARA EL DESARROLLO INTEGRADO DE NUEVAS HERRAMIENTAS APLICADAS AL CAMPO BIOMEDICO/
info:eu-repo/grantAgreement/EC/H2020/659121/EU/Antibacterial (Nano)medicines Development/
info:eu-repo/grantAgreement/MINECO//BIO2013-42619-P/ES/ESTRUCTURA, FUNCION, RECONOCIMIENTO Y EVOLUCION EN SEÑALIZACION CELULAR: DE LO BACTERIANO (SISTEMAS DE DOS COMPONENTES) A LO UNIVERSAL (DUTPASAS)/
info:eu-repo/grantAgreement/GVA//PROMETEOII%2F2014%2F029/ES/Genes, proteínas y rutas de señalización en enfermedades raras/
info:eu-repo/grantAgreement/GVA//PROMETEOII%2F2014%2F047/ES/Nuevas aproximaciones para el diseño de materiales de liberación controlada y la detección de compuestos peligrosos/
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Thanks:
This work was funded by FP7 ITN STARS-Scientific Training in Antimicrobial Research Strategies (Contract No. PITN-GA-2009-238490, J.M.W., A.M.), H2020 MSCA IF (AND-659121, N.V.), grant BIO2013-42619-P from the Ministerio ...[+]
Type: Artículo

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