De La Torre-Paredes, C.; Toscani, A.; Marín-Hernández, C.; Robson, JA.; Terencio, MC.; White, AJ.; Alcaraz, MJ.... (2017). Ex Vivo Tracking of Endogenous CO with a Ruthenium(II) Complex. Journal of the American Chemical Society. 139(51):18484-18487. https://doi.org/10.1021/jacs.7b11158
Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/148899
Title:
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Ex Vivo Tracking of Endogenous CO with a Ruthenium(II) Complex
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Author:
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De La Torre-Paredes, Cristina
Toscani, Anita
Marín-Hernández, Cristina
Robson, Jonathan A.
Terencio, M. Carmen
White, Andrew J.P.
Alcaraz, M. José
Wilton-Ely, James D.E.T.
Martínez-Máñez, Ramón
Sancenón Galarza, Félix
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UPV Unit:
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Universitat Politècnica de València. Departamento de Química - Departament de Química
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Issued date:
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Abstract:
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[EN] A two-photon fluorescent probe based on a ruthenium(II) vinyl complex is capable of selectively detecting carbon monoxide in cells and ex vivo using mice with a subcutaneous air pouch as a model for inflammation. This ...[+]
[EN] A two-photon fluorescent probe based on a ruthenium(II) vinyl complex is capable of selectively detecting carbon monoxide in cells and ex vivo using mice with a subcutaneous air pouch as a model for inflammation. This probe combines highly selective and sensitive ex vivo detection of endogenous CO in a realistic model with facile, inexpensive synthesis, and displays many advantages over the widely used palladium-based systems.
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Subjects:
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Carbon-Monoxide
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Living cells
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Fluorescent-Probe
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Selective detection
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Fluorogenic probes
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Heme Oxygenase-1
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Carbonylation
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Air
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Copyrigths:
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Reconocimiento (by)
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Source:
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Journal of the American Chemical Society. (issn:
0002-7863
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DOI:
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10.1021/jacs.7b11158
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Publisher:
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American Chemical Society
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Publisher version:
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https://doi.org/10.1021/jacs.7b11158
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Project ID:
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info:eu-repo/grantAgreement/MINECO//MAT2015-64139-C4-1-R/ES/NANOMATERIALES INTELIGENTES, SONDAS Y DISPOSITIVOS PARA EL DESARROLLO INTEGRADO DE NUEVAS HERRAMIENTAS APLICADAS AL CAMPO BIOMEDICO/
info:eu-repo/grantAgreement/Leverhulme Trust//RPG-2012-634/
info:eu-repo/grantAgreement/GVA//PROMETEOII%2F2014%2F047/ES/Nuevas aproximaciones para el diseño de materiales de liberación controlada y la detección de compuestos peligrosos/
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Thanks:
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The authors thank the Spanish government (Project MAT2015-64139-C4-1), the Generalitat Valencia (Project PROME-TEOII/2014/047), CIBER-BBN, IC Global Engagements fund, Santander Mobility Award. C.T. is grateful to the Spanish ...[+]
The authors thank the Spanish government (Project MAT2015-64139-C4-1), the Generalitat Valencia (Project PROME-TEOII/2014/047), CIBER-BBN, IC Global Engagements fund, Santander Mobility Award. C.T. is grateful to the Spanish Ministry of Science and Innovation, A.T. thanks the Leverhulme Trust (RPG-2012-634) and J.A.R. thanks the EPSRC, for PhD studentships.
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Type:
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Artículo
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