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Incidence, Outcomes, and Predictors of Ventricular Thrombus after Reperfused ST-Segment-Elevation Myocardial Infarction by Using Sequential Cardiac MR Imaging

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Incidence, Outcomes, and Predictors of Ventricular Thrombus after Reperfused ST-Segment-Elevation Myocardial Infarction by Using Sequential Cardiac MR Imaging

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dc.contributor.author Cambronero-Cortinas, E. es_ES
dc.contributor.author Bonanad, C. es_ES
dc.contributor.author Monmeneu, J.V. es_ES
dc.contributor.author López-Lereu, M.P. es_ES
dc.contributor.author Gavara-Doñate, Josep es_ES
dc.contributor.author De Dios, E. es_ES
dc.contributor.author Rios, C. es_ES
dc.contributor.author Perez, N. es_ES
dc.contributor.author Racugno, P. es_ES
dc.contributor.author Paya, A. es_ES
dc.contributor.author Escribano, D. es_ES
dc.contributor.author Minana, G. es_ES
dc.contributor.author Pellicer, M. es_ES
dc.contributor.author Cànoves, J. es_ES
dc.contributor.author Nunez, J. es_ES
dc.contributor.author Chorro, F.J. es_ES
dc.contributor.author Moratal, David es_ES
dc.contributor.author Bodi, V. es_ES
dc.date.accessioned 2020-07-31T03:31:44Z
dc.date.available 2020-07-31T03:31:44Z
dc.date.issued 2017-08 es_ES
dc.identifier.issn 0033-8419 es_ES
dc.identifier.uri http://hdl.handle.net/10251/149089
dc.description.abstract [EN] Purpose: To characterize the incidence, outcomes, and predictors of left ventricular (LV) thrombus by using sequential cardiac magnetic resonance (MR) imaging after ST-segment-elevation myocardial infarction (STEMI). Materials and Methods: Written informed consent was obtained from all patients, and the study protocol was approved by the committee on human research. In a cohort of 772 patients with STEMI, 392 (mean age, 58 years; range, 24-89 years) were retrospectively selected who were studied with cardiac MR imaging at 1 week and 6 months. Cardiac MR imaging guided the initiation and withdrawal of anticoagulants. Patients with LV thrombus at 6 months were restudied at 1 year. For predicting the occurrence of LV thrombus, a multiple regression model was applied. Results: LV thrombus was detected in 27 of 392 patients (7%): 18 (5%) at 1 week and nine (2%) at 6 months. LV thrombus resolved in 22 of 25 patients (88%) restudied within the first year. During a mean follow-up of 181 weeks 6 168, patients with LV thrombus displayed a very low rate of stroke (0%), peripheral embolism (0%), and severe hemorrhage (n = 1, 3.7%). LV ejection fraction (LVEF) less than 50% (P < .001) and anterior infarction (P = .008) independently helped predict LV thrombus. The incidence of LV thrombus was as follows: (a) nonanterior infarction, LVEF 50% or greater (one of 135, 1%); (b) nonanterior infarction, LVEF less than 50% (one of 50, 2%); (c) anterior infarction, LVEF 50% or greater (two of 92, 2%); and (d) anterior infarction, LVEF less than 50% (23 of 115, 20%) (P < .001 for the trend). Conclusion: Cardiac MR imaging contributes information for the diagnosis and therapy of LV thrombus after STEMI. Patients with simultaneous anterior infarction and LVEF less than 50% are at highest risk. (C) RSNA, 2017 es_ES
dc.description.sponsorship Study supported by Instituto de Salud Carlos III and FEDER (CB16/11/00486, PI14/00271, PIE15/00013) and Generalitat Valenciana (PROMETEO/2013/007). es_ES
dc.language Inglés es_ES
dc.publisher Radiological Society of North America es_ES
dc.relation.ispartof Radiology es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject.classification TECNOLOGIA ELECTRONICA es_ES
dc.title Incidence, Outcomes, and Predictors of Ventricular Thrombus after Reperfused ST-Segment-Elevation Myocardial Infarction by Using Sequential Cardiac MR Imaging es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1148/radiol.2017161898 es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//PIE15%2F00013/ES/A multidisciplinary project to advance in basic mechanisms, diagnosis, prediction, and prevention of cardiac damage in reperfused acute myocardial infarction/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//CB16%2F11%2F00486/ES/ENFERMEDADES CARDIOVASCULARES/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/MINECO//PI14%2F00271/ES/Fibrosis miocárdica tras un infarto de miocardio. Estudio traslacional para la innovación diagnóstica con resonancia magnética y para el entendimiento de los mecanismos reguladores/ es_ES
dc.relation.projectID info:eu-repo/grantAgreement/GVA//PROMETEO%2F2013%2F007/ es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Ingeniería Electrónica - Departament d'Enginyeria Electrònica es_ES
dc.description.bibliographicCitation Cambronero-Cortinas, E.; Bonanad, C.; Monmeneu, J.; López-Lereu, M.; Gavara-Doñate, J.; De Dios, E.; Rios, C.... (2017). Incidence, Outcomes, and Predictors of Ventricular Thrombus after Reperfused ST-Segment-Elevation Myocardial Infarction by Using Sequential Cardiac MR Imaging. Radiology. 284(2):372-380. https://doi.org/10.1148/radiol.2017161898 es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1148/radiol.2017161898 es_ES
dc.description.upvformatpinicio 372 es_ES
dc.description.upvformatpfin 380 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 284 es_ES
dc.description.issue 2 es_ES
dc.identifier.pmid 28253107 es_ES
dc.relation.pasarela S\353073 es_ES
dc.contributor.funder Generalitat Valenciana es_ES
dc.contributor.funder European Regional Development Fund es_ES
dc.contributor.funder Ministerio de Economía y Competitividad es_ES


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