Martínez, H.; Barrachina, S.; Castillo, M.; Quintana Ortí, ES.; Rambla De Argila, J.; Farre, X.; Navarro, A. (2018). FaST-LMM for two-way Epistasis tests on high performance clusters. Journal of Computational Biology. 25(8):862-870. https://doi.org/10.1089/cmb.2018.0087
Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/149916
Title:
|
FaST-LMM for two-way Epistasis tests on high performance clusters
|
Author:
|
Martínez, Héctor
Barrachina, Sergio
Castillo, Maribel
Quintana Ortí, Enrique Salvador
Rambla de Argila, Jordi
Farre, Xavier
Navarro, Arcadi
|
UPV Unit:
|
Universitat Politècnica de València. Departamento de Informática de Sistemas y Computadores - Departament d'Informàtica de Sistemes i Computadors
|
Issued date:
|
|
Abstract:
|
[EN] We introduce a version of the epistasis test in FaST-LMM for clusters of multithreaded processors. This new software maintains the sensitivity of the original FaST-LMM while delivering acceleration that is close to ...[+]
[EN] We introduce a version of the epistasis test in FaST-LMM for clusters of multithreaded processors. This new software maintains the sensitivity of the original FaST-LMM while delivering acceleration that is close to linear on 12-16 nodes of two recent platforms, with respect to improved implementation of FaST-LMM presented in an earlier work. This efficiency is attained through several enhancements on the original single-node version of FaST-LMM, together with the development of a message passing interface (MPI)-based version that ensures a balanced distribution of the workload as well as a multigraphics processing unit (GPU) module that can exploit the presence of multiple GPUs per node.
[-]
|
Subjects:
|
Clusters of computers
,
Epistasis
,
FaST-LMM
,
Genome-wide association studies (GWAS)
,
GPUs
,
Multicore processors
|
Copyrigths:
|
Reserva de todos los derechos
|
Source:
|
Journal of Computational Biology. (issn:
1066-5277
)
|
DOI:
|
10.1089/cmb.2018.0087
|
Publisher:
|
Mary Ann Liebert
|
Publisher version:
|
https://doi.org/10.1089/cmb.2018.0087
|
Project ID:
|
MINECO/TIN2014-53495-R
MINECO/TIN2017-82972-R
WT/076113
|
Thanks:
|
The researchers from the Universitat Jaume I were supported by projects TIN2014-53495-R and TIN2017-82972-R of the MINECO and FEDER.
|
Type:
|
Artículo
|