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Characterization of the lowest singlet and triplet states of S-Flurbiprofen

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Characterization of the lowest singlet and triplet states of S-Flurbiprofen

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dc.contributor.author Jiménez Molero, María Consuelo es_ES
dc.contributor.author Miranda Alonso, Miguel Ángel es_ES
dc.contributor.author Tormos Faus, Rosa Esperanza es_ES
dc.contributor.author Vayá Pérez, Ignacio es_ES
dc.date.accessioned 2020-09-18T03:35:33Z
dc.date.available 2020-09-18T03:35:33Z
dc.date.issued 2004 es_ES
dc.identifier.issn 1474-905X es_ES
dc.identifier.uri http://hdl.handle.net/10251/150337
dc.description.abstract [EN] The photophysical properties of S-flurbiprofen [S-2-fluoro-alpha-methyl-4-biphenylacetic acid], a nonsteroidal anti-inflammatory drug, have been examined using steady-state and time-resolved spectroscopic techniques. The energy of its first singlet excited state is 99 kcal mol(-1). The fluorescence quantum yields and lifetimes (at 300 nm) have been determined in acetonitrile, methanol, hexane and PBS; they are in the range 0.15 < &phi;(F) < 0.33 and 0.7 < &tau;(F) < 2.0 ns. The intersystem crossing quantum yields are between 0.45 and 0.71; the lambda(max) of the T-T absorption is 360 nm, and the triplets live from 15 to 106 mus. Steady state photolysis in aqueous medium leads to S-2-hydroxy-alpha-methyl-4-biphenylacetic acid via photonucleophilic aromatic substitution, in addition to the photodecarboxylation products observed in organic solvents. es_ES
dc.description.sponsorship Financial support from the MCYT (BQU2001-2725), the Generalitat Valenciana (Grupos03/82 and GV04B/468) and the U.P.V. (Project 2003-0522) is gratefully acknowledged. I. V. thanks Fundación José y Ana Royo for a fellowship. es_ES
dc.language Inglés es_ES
dc.publisher The Royal Society of Chemistry es_ES
dc.relation UPV/PI 2003-0522 es_ES
dc.relation GENERALITAT VALENCIANA/GV04B/468 es_ES
dc.relation MINISTERIO DE CIENCIA Y TECNOLOGIA/BQU2001-2725 es_ES
dc.relation.ispartof Photochemical & Photobiological Sciences es_ES
dc.rights Reserva de todos los derechos es_ES
dc.subject.classification QUIMICA ORGANICA es_ES
dc.title Characterization of the lowest singlet and triplet states of S-Flurbiprofen es_ES
dc.type Artículo es_ES
dc.identifier.doi 10.1039/b408530b es_ES
dc.rights.accessRights Abierto es_ES
dc.contributor.affiliation Universitat Politècnica de València. Departamento de Química - Departament de Química es_ES
dc.description.bibliographicCitation Jiménez Molero, MC.; Miranda Alonso, MÁ.; Tormos Faus, RE.; Vayá Pérez, I. (2004). Characterization of the lowest singlet and triplet states of S-Flurbiprofen. Photochemical & Photobiological Sciences. 3(11-12):1038-1041. https://doi.org/10.1039/b408530b es_ES
dc.description.accrualMethod S es_ES
dc.relation.publisherversion https://doi.org/10.1039/b408530b es_ES
dc.description.upvformatpinicio 1038 es_ES
dc.description.upvformatpfin 1041 es_ES
dc.type.version info:eu-repo/semantics/publishedVersion es_ES
dc.description.volume 3 es_ES
dc.description.issue 11-12 es_ES
dc.relation.pasarela S\25380 es_ES
dc.contributor.funder GENERALITAT VALENCIANA es_ES
dc.contributor.funder MINISTERIO DE CIENCIA Y TECNOLOGIA es_ES
dc.contributor.funder Universitat Politècnica de València es_ES


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