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dc.contributor.author | Revert Tomás, Ana | es_ES |
dc.contributor.author | Garelli, Fabricio | es_ES |
dc.contributor.author | Picó, Jesús | es_ES |
dc.contributor.author | De Battista, Hernan | es_ES |
dc.contributor.author | Rossetti, Paolo | es_ES |
dc.contributor.author | Bondía Company, Jorge | es_ES |
dc.date.accessioned | 2020-09-19T03:34:09Z | |
dc.date.available | 2020-09-19T03:34:09Z | |
dc.date.issued | 2013-08 | es_ES |
dc.identifier.issn | 0018-9294 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/150435 | |
dc.description.abstract | [EN] The artificial pancreas aims at the automatic deliv-ery of insulin for glycemic control in patients with type 1 diabetes, i.e., closed-loop glucose control. One of the challenges of the arti-ficial pancreas is to avoid controller overreaction leading to hypo-glycemia, especially in the late postprandial period. In this study, an original proposal based on sliding mode reference conditioning ideas is presented as a way to reduce hypoglycemia events induced by a closed-loop glucose controller. The method is inspired in the intuitive advantages of two-step constrained control algorithms. It acts on the glucose reference sent to the main controller shaping it so as to avoid violating given constraints on the insulin-on-board. Some distinctive features of the proposed strategy are that 1) it provides a safety layer which can be adjusted according to medical criteria; 2) it can be added to closed-loop controllers of any nature; 3) it is robust against sensor failures and overestimated prandial insulin doses; and 4) it can handle nonlinear models. The method is evaluated in silico with the ten adult patients available in the FDA-accepted UVA simulator. | es_ES |
dc.description.sponsorship | This work was supported in part by the FEDER-CICYT under Grant DPI2008-06880-C03-01, Grant DPI2011-28112-C04-01, and Grant DPI2010-20764-C02, in part by the European Union Seventh Framework Programme (FP7/2007-2013) under Grant FP7-PEOPLE-2009-IEF Ref 252085, and in part by the Argentinian Government under Grant ANPCyT PICT-2011-0888, Grant CONICET PIP112-2011-00361, and Grant UNLP I164. The work of A. Revert was supported by the Spanish Ministry of Science and Innovation fellowship under Grant FPI BES-2009-020327. | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Institute of Electrical and Electronics Engineers | es_ES |
dc.relation.ispartof | IEEE Transactions on Biomedical Engineering | es_ES |
dc.rights | Reserva de todos los derechos | es_ES |
dc.subject | Artificial pancreas | es_ES |
dc.subject | Glucose control | es_ES |
dc.subject | Hypo-glycemia | es_ES |
dc.subject | Insulin-on-board | es_ES |
dc.subject | Reference conditioning | es_ES |
dc.subject | Safety | es_ES |
dc.subject | Sliding mode (SM). | es_ES |
dc.subject.classification | INGENIERIA DE SISTEMAS Y AUTOMATICA | es_ES |
dc.title | Safety Auxiliary Feedback Element for the Artificial Pancreas in Type 1 Diabetes | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1109/TBME.2013.2247602 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/EC/FP7/252085/EU/Seeking solutions for the artificial pancreas: new methods for improving continuous glucose monitoring and closed-loop postprandial glycaemic control./ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/ANPCyT//PICT-2011-0888/AR/Sistemas conmutados de control. Aplicación al control de procesos y sistemas con restricciones/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/CONICET//PIP 112201100361/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/UNLP//I164/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MICINN//DPI2010-20764-C02-01/ES/NUEVAS ESTRATEGIAS DE CONTROL GLUCEMICO POSTPRANDIAL MEDIANTE TERAPIA CON BOMBA DE INSULINA EN DIABETES TIPO 1/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MICINN//BES-2009-020327-2/ES/BES-2009-020327-2/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MICINN//DPI2011-28112-C04-01/ES/MONITORIZACION, INFERENCIA, OPTIMIZACION Y CONTROL MULTI-ESCALA: DE CELULAS A BIORREACTORES/ | es_ES |
dc.rights.accessRights | Cerrado | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Ingeniería de Sistemas y Automática - Departament d'Enginyeria de Sistemes i Automàtica | es_ES |
dc.description.bibliographicCitation | Revert Tomás, A.; Garelli, F.; Picó, J.; De Battista, H.; Rossetti, P.; Bondía Company, J. (2013). Safety Auxiliary Feedback Element for the Artificial Pancreas in Type 1 Diabetes. IEEE Transactions on Biomedical Engineering. 60(8):2113-2122. https://doi.org/10.1109/TBME.2013.2247602 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1109/TBME.2013.2247602 | es_ES |
dc.description.upvformatpinicio | 2113 | es_ES |
dc.description.upvformatpfin | 2122 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 60 | es_ES |
dc.description.issue | 8 | es_ES |
dc.identifier.pmid | 23428611 | es_ES |
dc.relation.pasarela | S\254392 | es_ES |
dc.contributor.funder | Universidad Nacional de La Plata, Argentina | es_ES |
dc.contributor.funder | Agencia Nacional de Promoción Científica y Tecnológica, Argentina | es_ES |
dc.contributor.funder | Consejo Nacional de Investigaciones Científicas y Técnicas, Argentina | es_ES |
dc.contributor.funder | Ministerio de Ciencia e Innovación | es_ES |