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Diastereoselective Michael addition of (S)-mandelic acid enolate to 2-arylidene-1,3-diketones: enantioselective diversity-oriented synthesis of densely substituted pyrazoles

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Diastereoselective Michael addition of (S)-mandelic acid enolate to 2-arylidene-1,3-diketones: enantioselective diversity-oriented synthesis of densely substituted pyrazoles

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Blay, G.; Fernández, I.; Molina, E.; Muñoz Roca, MDC.; Pedro, JR.; Vila, C. (2006). Diastereoselective Michael addition of (S)-mandelic acid enolate to 2-arylidene-1,3-diketones: enantioselective diversity-oriented synthesis of densely substituted pyrazoles. Tetrahedron. 62(34):8069-8076. https://doi.org/10.1016/j.tet.2006.06.009

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Title: Diastereoselective Michael addition of (S)-mandelic acid enolate to 2-arylidene-1,3-diketones: enantioselective diversity-oriented synthesis of densely substituted pyrazoles
Author: Blay, Gonzalo Fernández, Isabel Molina, Eva Muñoz Roca, María Del Carmen Pedro, Jose R. Vila, Carlos
UPV Unit: Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada
Issued date:
Abstract:
[EN] A diversity-oriented approach to enantiomerically pure densely substituted pyrazoles, ¿-aryl-¿-pyrazolylatrolactic acid and ¿-aryl-¿-pyrazolylacetophenones has been developed. The approach utilises the conjugated ...[+]
Copyrigths: Cerrado
Source:
Tetrahedron. (issn: 0040-4020 )
DOI: 10.1016/j.tet.2006.06.009
Publisher:
Elsevier
Publisher version: https://doi.org/10.1016/j.tet.2006.06.009
Project ID:
MCYT/BQU2001-3017
GV/GV05/10
GV/03/168
Thanks:
Financial supports from the Spanish Government MEC (BQU2001-3017) and from Generalitat Valenciana (Grupos 03/168 and GV05/10) are acknowledged.
Type: Artículo

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