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Mechanical unfolding of long human telomeric RNA (TERRA)

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Mechanical unfolding of long human telomeric RNA (TERRA)

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Garavís, M.; Bocanegra, R.; Herrero-Galán, E.; González, C.; Villasante, A.; Arias-Gonzalez, JR. (2013). Mechanical unfolding of long human telomeric RNA (TERRA). Chemical Communications. 49(57):6397-6399. https://doi.org/10.1039/c3cc42981d

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Title: Mechanical unfolding of long human telomeric RNA (TERRA)
Author: Garavís, M. Bocanegra, R. Herrero-Galán, E. González, C. Villasante, A. Arias-Gonzalez, J. R.
UPV Unit: Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada
Issued date:
Abstract:
[EN] We report the first single molecule investigation of TERRA molecules. By using optical-tweezers and other biophysical techniques, we have found that long RNA constructions of up to 25 GGGUUA repeats form higher order ...[+]
Subjects: G-quadruplex , TERRA , Single-molecule , Optical tweezers , Unfolding , Stability
Copyrigths: Reserva de todos los derechos
Source:
Chemical Communications. (issn: 1359-7345 )
DOI: 10.1039/c3cc42981d
Publisher:
The Royal Society of Chemistry
Publisher version: https://doi.org/10.1039/c3cc42981d
Thanks:
This work was supported by grants from the Spanish Ministry of Science and Innovation (grants RYC2007-01765 to JRA-G, BFU2011-30295-C02-01 to AV, and CTQ2010-21567-C02-02 to CG). MG was supported by the FPI fellowship ...[+]
Type: Artículo

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