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dc.contributor.author | Araujo, J. | es_ES |
dc.contributor.author | Padrao, J. | es_ES |
dc.contributor.author | Silva, J. P. | es_ES |
dc.contributor.author | Dourado, F. | es_ES |
dc.contributor.author | Correia, D. M. | es_ES |
dc.contributor.author | Botelho, G. | es_ES |
dc.contributor.author | Gómez Ribelles, José Luís | es_ES |
dc.contributor.author | Lanceros-Mendez, S. | es_ES |
dc.contributor.author | Sencadas, V. | es_ES |
dc.date.accessioned | 2020-10-22T03:32:30Z | |
dc.date.available | 2020-10-22T03:32:30Z | |
dc.date.issued | 2014-06 | es_ES |
dc.identifier.issn | 0947-8396 | es_ES |
dc.identifier.uri | http://hdl.handle.net/10251/152812 | |
dc.description.abstract | [EN] Elastin isolated from fresh bovine ligaments was dissolved in a mixture of 1,1,1,3,3,3-Hexafluoro-2-propanol and water were electrospun into fiber membranes under different processing conditions. Fiber mats of randomly and aligned fibers were obtained with fixed and rotating ground collectors and fibrils were composed by thin ribbons whose width depends on electrospinning conditions; fibrils with 721 nm up to 2.12 ¿m width were achieved. After cross-linking with glutaraldehyde, ¿-elastin can uptake as much as 1700 % of PBS solution and a slight increase on fiber thickness was observed. The glass transition temperature of electrospun fiber mats was found to occur at ~80 °C. Moreover, ¿-Elastin showed to be a perfect elastomeric material, and no mechanical hysteresis was found in cycle mechanical measurements. The elastic modulus obtained for random and aligned fibers mats in a PBS solution was 330±10 kPa and 732±165 kPa, respectively. Finally, the electrospinning and cross-linking process does not inhibit MC-3T3-E1 cell adhesion. Cell culture results showed good cell adhesion and proliferation in the cross-linked elastin fiber mats. | es_ES |
dc.description.sponsorship | This work is funded by FEDER funds through the "Programa Operacional Factores de Competitividade-COMPETE" and by national funds arranged by FCT-Fundacao para a Ciencia e a Tecnologia, project references NANO/NMed-SD/0156/2007, PTDC/CTM-NAN/112574/2009, and PEST-C/FIS/UI607/2011. The authors also thank funding from "Matepro-Optimizing Materials and Processes", ref. "NORTE-07-0124-FEDER-000037", cofunded by the "Programa Operacional Regional do Norte" (ON.2-O Novo Norte), under the "Quadro de Referencia Estrategico Nacional" (QREN), through the "Fundo Europeu de Desenvolvimento Regional" (FEDER). The authors also thank support from the COST Action MP1003, 2010 'European Scientific Network for Artificial Muscles'. VS, JP, JS, and DMC thank the FCT for the SFRH/BD/48708/2008, SFRH/BD/64901/2009, SFRH/BPD/64958/2009 and SFRH/BPD/63148/2009, and SFRH/BD/82411/2011 grants, respectively. JLGR acknowledges the support of the Spanish Ministry of Science and Innovation through project No. MAT2010-21611-C03-01 (including the FEDER financial support). CIBER-BBN is an initiative funded by the VI National R&D&i Plan 2008-2011, Iniciativa Ingenio 2010, Consolider Program, CIBER Actions and financed by the Instituto de Salud Carlos III with assistance from the European Regional Development Fund. | es_ES |
dc.language | Inglés | es_ES |
dc.publisher | Springer-Verlag | es_ES |
dc.relation.ispartof | Applied Physics A | es_ES |
dc.rights | Reserva de todos los derechos | es_ES |
dc.subject.classification | MAQUINAS Y MOTORES TERMICOS | es_ES |
dc.title | Processing and characterization of alpha-elastin electrospun membranes | es_ES |
dc.type | Artículo | es_ES |
dc.identifier.doi | 10.1007/s00339-013-7984-9 | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/COST//MP1003/EU/European Scientific Network for Artificial Muscles (ESNAM)/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/112574/PT/PROTSENSOR - A novel pressure sensor network system for static and dynamic measurement. Application to the limb/prosthesis pressure mapping./ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F48708%2F2008/PT/MATERIAIS INTELIGENTES ELECTROACTIVOS PARA APLICAÇÕES TEXTEIS E BIOMÉDICAS/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT//NORTE-07-0124-FEDER-000037/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F64901%2F2009/PT/DESENVOLVIMENTO E CARACTERIZAÇÃO DE NOVOS FILMES EDÍVEIS COM PROPRIEDADES ANTI-MICROBIANAS PARA EMBALAGENS ALIMENTARES/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT//PEst-C%2FFIS%2FUI607%2F2011/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F82411%2F2011/PT/SCAFFOLDS TRIDIMENSIONAIS BASEADOS EM NNANOFIBRAS ELECTROACTIVAS BIODEGRADÁVEIS PARA APLICAÇÃO EM ENGENHARIA DE TECIDOS/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/MICINN//MAT2010-21611-C03-01/ES/MATERIALES BIOESTABLES Y BIOREABSORBIBLES A LARGO PLAZO COMO SOPORTES MACROPOROSOS PARA LA REGENERACION DEL CARTILAGO ARTICULAR/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F63148%2F2009/PT/ELECTROACTIVE MATERIALS BASED POROUS MEMBRANES AND SCAFFOLDS FOR BIOMEDICAL APPLICATIONS/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F64958%2F2009/PT/ENGINEERING TISSUES WITH BACTERIAL CELLULOSE/ | es_ES |
dc.relation.projectID | info:eu-repo/grantAgreement/FEDER//FEDER/NORTE-07-0124-FEDER-000037/2013/EU/Matepro Optimizing Materials and Processes/ | |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT/5876-PPCDTI/109368/PT/“Smart joint implants using bionanocomposites-(SIMBIO)”/ | |
dc.relation.projectID | info:eu-repo/grantAgreement/FCT//PEST-C/FIS%2FUI607%2F2011/PT/ | |
dc.rights.accessRights | Cerrado | es_ES |
dc.contributor.affiliation | Universitat Politècnica de València. Departamento de Termodinámica Aplicada - Departament de Termodinàmica Aplicada | es_ES |
dc.description.bibliographicCitation | Araujo, J.; Padrao, J.; Silva, JP.; Dourado, F.; Correia, DM.; Botelho, G.; Gómez Ribelles, JL.... (2014). Processing and characterization of alpha-elastin electrospun membranes. Applied Physics A. 115(4):1291-1298. https://doi.org/10.1007/s00339-013-7984-9 | es_ES |
dc.description.accrualMethod | S | es_ES |
dc.relation.publisherversion | https://doi.org/10.1007/s00339-013-7984-9 | es_ES |
dc.description.upvformatpinicio | 1291 | es_ES |
dc.description.upvformatpfin | 1298 | es_ES |
dc.type.version | info:eu-repo/semantics/publishedVersion | es_ES |
dc.description.volume | 115 | es_ES |
dc.description.issue | 4 | es_ES |
dc.relation.pasarela | S\284990 | es_ES |
dc.contributor.funder | European Regional Development Fund | es_ES |
dc.contributor.funder | European Cooperation in Science and Technology | es_ES |
dc.contributor.funder | Fundação para a Ciência e a Tecnologia, Portugal | es_ES |
dc.contributor.funder | Ministerio de Ciencia e Innovación | es_ES |
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