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DNA synthesis determines the binding mode of the human mitochondrial single-stranded DNA-binding protein

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DNA synthesis determines the binding mode of the human mitochondrial single-stranded DNA-binding protein

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Morin, J.; Cerrón, F.; Jarillo, J.; Beltran-Heredia, E.; Ciesielski, G.; Arias-Gonzalez, JR.; Kaguni, L.... (2017). DNA synthesis determines the binding mode of the human mitochondrial single-stranded DNA-binding protein. Nucleic Acids Research. 45(12):7237-7248. https://doi.org/10.1093/nar/gkx395

Por favor, use este identificador para citar o enlazar este ítem: http://hdl.handle.net/10251/153374

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Title: DNA synthesis determines the binding mode of the human mitochondrial single-stranded DNA-binding protein
Author: Morin, J.A. Cerrón, F. Jarillo, J. Beltran-Heredia, E. Ciesielski, G.L. Arias-Gonzalez, J. R. Kaguni, L.S. Cao, F.J. Ibarra, B.
UPV Unit: Universitat Politècnica de València. Departamento de Física Aplicada - Departament de Física Aplicada
Issued date:
Abstract:
[EN] Single-stranded DNA-binding proteins (SSBs) play a key role in genome maintenance, binding and organizing single-stranded DNA (ssDNA) intermediates. Multimeric SSBs, such as the human mitochondrial SSB (HmtSSB), present ...[+]
Subjects: DNA , DNA polymerase , Replication , Single-molecule
Copyrigths: Reconocimiento - No comercial (by-nc)
Source:
Nucleic Acids Research. (issn: 0305-1048 )
DOI: 10.1093/nar/gkx395
Publisher:
Oxford University Press
Publisher version: https://doi.org/10.1093/nar/gkx395
Project ID:
MINECO/FIS2010-17440
...[+]
MINECO/FIS2010-17440
MINECO/BFU2012-31825
MINECO/MAT2015-71806-R
MINECO/FIS2015-67765-R
MINECO/BFU2015-63714-R
MECD/FPU13/02934
MECD/FPU13/02826
NIH/GM45925
Santander Universidades /CT45/15-CT46/15
[-]
Thanks:
We are grateful to Prof. M. Salas laboratory (CBMSO-CSIC) for generously providing the Phi29 DNA polymerase and to Juan P. García Villaluenga (UCM) for useful discussions. Spanish Ministry of Economy and Competitiveness ...[+]
Type: Artículo

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